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Cryo-EM Reveals Crucial Electrical Switch in Brain

Scientists using cryo-EM have revealed the structure of a critical receptor (AMPA) in the brain associated with learning, memory, behavior and mood. The research was also the first to reveal the structure of AMPA receptors in a natural state, a discovery that could lead to new insight about the mechanism...

Researchers Discover Water that Never Freezes

Can water reach -263°C without turning into ice? The answer is yes, according to a group of physicists and chemists from ETH Zurich and the University of Zurich who identified an unusual way to not only prevent water from forming ice crystals while at extreme sub-zero temperatures but to also...

Working Together as a “virtual telescope,” Observatories Around the World Produce First Direct Images of a Black Hole

MIT News reported on April 10 that an international team of over 200 astronomers had captured the first direct images of a black hole. They accomplished this remarkable feat by coordinating the power of nine major radio observatories on four continents, to work together as a virtual, Earth-sized telescope. In...

Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Latest in Defining Cryogenics

Liquid Hydrogen

Hydrogen becomes a liquid at 20K and 1 bar. Liquid hydrogen (LH2) is an important substance in industry, transportation and research. Industrial uses of hydrogen include applications in the electronics, glass, chemical and metal processing fields. In these applications, the hydrogen is generally used as a room temperature gas but...

Superconducting Radiofrequency Cavities

Superconducting radio frequency (SRF) cavities represent an important application of cryogenics and superconductivity. SRF cavities are a technology for accelerating charged particle beams via the transfer of radiofrequency (RF) energy to the beams via resonant structures. As such, they are frequently found in large particle accelerators used for scientific research....

Thermal Radiation Shields

Actively cooled thermal radiation shields are a common feature of cryostats whose lowest temperature is less than 77K. These shields, which typically operate at temperatures between that of LN2 and 40K, block thermal radiation from higher temperatures from reaching lower temperature cryogenic components or fluids. Since the heat radiated from...

Latest in Cryo Central

Wind Tunnels

Dr. Robert Kilgore The development of the cryogenic wind tunnel is one of many significant breakthroughs in both cryogenics and wind-tunnel technology made during the past millennium. Interest in the development of high-speed commercial and military aircraft resulted in a review of problems of flow simulation in transonic wind tunnels...

History of Cryogenics

From the Fall 1999 issue of Cold Facts magazine Millennium Breakthroughs A variety of CSA members give different perspectives on the past millennium: What were the most significant breakthroughs in cryogenics during the past millennium? Prof. R.G. Scurlock, Kryos Technology, scurlock@soton.ac.uk (“Breakthrough” = way through obstacles — Oxford English Dictionary)...

Cryobiology

Andreas Sputtek Past President Society for Cryobiology sputtek@uke.uni-hamburg.de or http://www.sputtek.de/. The word cryobiology (from the Greek words “cryo” = cold, “bios” = life, and “logos” = science) literally signifies the science of life at low temperatures. In practice, this field comprises the study of any biological material or system (e.g.,...

Cryogenic Insulation

James E. Fesmire Cryogenics Test Laboratory NASA Kennedy Space Center james.e.fesmire@nasa.gov Introduction In today’s world, the use of cryogenics and low-temperature refrigeration is taking a more and more significant role. From the food industry, transportation, energy, and medical applications to the Space Shuttle, cryogenic liquids must be stored, handled, and...

Latest in Ask the Experts

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...

Separated layers of ice over a pipe

I want to know that why there are different layers of ice over a pipe carrying a cryogenic fluid, each layer separated with clear marks / lines? What do these layers signify?

Using nitrogen as a cryogen

Is it possible to achieve -200˚C using nitrogen as a cryogen?

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