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Technifab Hoses
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Designing Cryogenic Piping Systems for the Demands of Modern Life Science Labs

As life science facilities become more advanced and specialized, the infrastructure behind them must evolve to meet increasing demands for efficiency, precision, and cost-effectiveness. Technifab Products, Inc., in partnership with CryoWorks, is leading the way in cryogenic piping solutions for the biotech, pharmaceutical, and research sectors—supporting applications ranging from cryosurgery...
July 9, 2025
Quantum Design
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Quantum Design Signs Agreement to Acquire NanoScience Division ofOxford Instruments

Quantum Design, a leading developer of cryogenic measurement systems based in San Diego, California, has announced a definitive agreement to acquire the NanoScience Division of Oxford Instruments. Located in Oxfordshire, United Kingdom, NanoScience is a global innovator in ultra-low-temperature cryogenic instrumentation. The acquisition, expected to close by the end of...
July 9, 2025
A Soyuz rocket launches to the International Space Station with Expedition 73 crew members including NASA astronaut Jonny Kim on Tuesday, April 8, 2025, at the Baikonur Cosmodrome in Kazakhstan. Photo ©NASA/Joel Kowsky
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Stainless VJP Enable Cryogenic Liquid Supply Chains in Space and on Earth

A Soyuz rocket launches to the International Space Station with Expedition 73 crew members including NASA astronaut Jonny Kim on Tuesday, April 8, 2025, at the Baikonur Cosmodrome in Kazakhstan. Photo ©NASA/Joel Kowsky What do space exploration and the Hydrogen Economy have in common? A need to transport large volumes...
July 9, 2025
News

Google and Commonwealth Fusion Systems Sign Strategic Partnership

Credit: Commonwealth Fusion Systems Google and Commonwealth Fusion Systems (CFS) today announced a new global milestone, a bold partnership to develop, deploy and scale clean, secure fusion power. Google signed a power purchase agreement (PPA) for 200 megawatts (MW) of electricity from CFS’ inaugural ARC power plant, which CFS expects...
June 30, 2025
Image source: Taihan/SuperNode
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Korean Cable Corp Signs Deal Next-Gen Superconductors

Image source: Taihan/SuperNodeA leading Korean cable company has signed a deal with an Irish firm to develop “next-generation” superconducting cables for the offshore wind industry. Taihan will work with Dublin-based SuperNode on the design and roll out of polymer-based transmission cables which promise to “significantly” enhance efficiency and simplify installation...
June 24, 2025
Modifying gas chromatography systems with cryogenic technologies Subscribe for newsletter updates Researchers at Monash University in Clayton, Australia, have developed a new 3D-printed device for gas chromatography (GC), demonstrating its effectiveness in carrying out multidimensional and enantioselective separations. GC has long been central to chemical analysis, particularly for mixtures of volatile compounds. However, its resolution can be insufficient for separating complex mixtures. Scientists have addressed this limitation with techniques such as multidimensional gas chromatography (MDGC) and comprehensive two-dimensional gas chromatography (GC × GC), which both require modulation devices. Thermal modulators, among the earliest developed, remain widely used. In this study, the researchers designed a stainless steel 3D-printed device to function as a cold trapping assembly when cooled with liquid CO₂. Its operational principle mirrors that of a longitudinally modulated cryogenic system (LMCS). Cryogenic technologies have precedent in chromatography, offering the capacity to remobilise trapped components, thereby enabling new analytical approaches. When integrated with GC, such devices allow analysts to apply advanced separation techniques. The team detailed the enclosure design and assessed its performance for collecting and rapidly remobilising volatile organic compounds (VOCs). Modulation period precision was evaluated, yielding a maximum error of 8 microseconds and an average variation of less than 1 nanosecond across 10,000 successive modulations. Using a C5–C9 alkane series, the system was shown to effectively trap analytes, with peaks achieving a full width at half height (FWHH) as low as 65 milliseconds. The maximum trapping time was determined using hexane, with the modulator retaining the compound for up to 9 seconds at 100 °C before breakthroughs occurred. The system was also used to investigate the enantioselective separation of limonene, a compound derived from citrus peel oils. Although only one chiral column was used, different column lengths (ranging from 20 cm to 5.0 m) were drawn through the modulator. These effectively acted as enantioselective second-dimension (2D) columns. Injected (R,S)-limonene enantiomers were collected simultaneously and then rapidly transferred to the 2D column. The 3D-printed modulator successfully trapped hexane, enabling modulation periods of up to 8 seconds. This was achieved at oven temperatures of up to 100 °C. While higher temperatures were not tested, the researchers suggest that hexane modulation beyond this point is likely feasible. Ultimately, the study demonstrated the feasibility of comprehensive two-dimensional GC using 3D-printed modulators with a tea tree oil sample. Although 2D retention times exceeded optimal limits for GC × GC under the conditions tested, the authors propose that further refinement of columns and methods could yield improved separation.
News

Modifying Gas Chromatography Systems with Cryogenic Technologies

Clayton Campus, Melbourne, Victoria. Credit: Montash University, Australia Researchers at Monash University in Clayton, Australia, have developed a new 3D-printed device for gas chromatography (GC), demonstrating its effectiveness in carrying out multidimensional and enantioselective separations. GC has long been central to chemical analysis, particularly for mixtures of volatile compounds. However,...
June 24, 2025

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Latest in Defining Cryogenics
Defining Cryogenics

Dewar

A dewar is a type of cryostat named after Sir James Dewar, the researcher who first developed the concept of a vacuum insulated container with silvered walls to reflect thermal radiation. Dewar was the first to liquefy hydrogen, and he created the device to store his discovery. The thermos bottle...
June 18, 2018
Defining Cryogenics

Stirling and Gifford-McMahon Cryocoolers

Stirling and Gifford-McMahon (GM) cryocoolers are two of the most commonly used cryocoolers in cryogenics. Both devices have a significant industrial base and operate at a wide range of temperatures and capacities. The thermodynamic cycles for both of these cryocoolers are quite similar. The Stirling cycle consists of a compressor,...
May 2, 2018
Defining Cryogenics

Liquefied Natural Gas (LNG)

A significant commercial application of cryogenics is the liquefaction, transport and storage of natural gas. Liquefied Natural Gas (LNG) is generally 95 percent methane with a few percent ethane and much lower concentrations of propane and butane. LNG liquefies at 111.6 K. Unlike many applications of cryogenics, the motivation for...
March 6, 2018
Latest in Cryo Central
Cryo Central

Wind Tunnels

Dr. Robert Kilgore The development of the cryogenic wind tunnel is one of many significant breakthroughs in both cryogenics and wind-tunnel technology made during the past millennium. Interest in the development of high-speed commercial and military aircraft resulted in a review of problems of flow simulation in transonic wind tunnels...
April 18, 2008
Cryo Central

History of Cryogenics

From the Fall 1999 issue of Cold Facts magazine Millennium Breakthroughs A variety of CSA members give different perspectives on the past millennium: What were the most significant breakthroughs in cryogenics during the past millennium? Prof. R.G. Scurlock, Kryos Technology, scurlock@soton.ac.uk (“Breakthrough” = way through obstacles — Oxford English Dictionary)...
April 18, 2008
Cryo Central

Cryobiology

Andreas Sputtek Past President Society for Cryobiology sputtek@uke.uni-hamburg.de or http://www.sputtek.de/. The word cryobiology (from the Greek words “cryo” = cold, “bios” = life, and “logos” = science) literally signifies the science of life at low temperatures. In practice, this field comprises the study of any biological material or system (e.g.,...
April 18, 2008
Cryo Central

Cryogenic Insulation

James E. Fesmire Cryogenics Test Laboratory NASA Kennedy Space Center james.e.fesmire@nasa.gov Introduction In today’s world, the use of cryogenics and low-temperature refrigeration is taking a more and more significant role. From the food industry, transportation, energy, and medical applications to the Space Shuttle, cryogenic liquids must be stored, handled, and...
April 18, 2008
Latest in Ask the Experts
Ask the Experts

In search of a calculation for designing a cryostat

I am a final year physics student at the University of Birmingham, and as part of a group I am currently designing a cryostat. One of the calculations I need to make (very soon!) is how much heat will be conducted down the walls. All information I have found so...
August 1, 2008
Ask the Experts

Safety of ethylene glycol and pressurized oxygen

We are reviewing the product design of liquid filled differential level gauges and want to insure that they meet the industry requirements. The former license owner had authorized that a fill fluid of ethylene glycol (68%) and distilled water (32%) could be used for oxygen service up to 500 psi....
August 1, 2008