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Doctor Advances Cryopreservation in Heart Regeneration and Organ Transplantation

At Harvard Medical School and Massachusetts General Hospital, Dr. Rasha Al-attar’s research is at the forefront of advancing heart regeneration and organ transplantation. Initially focusing on stem cell-derived cardiomyocyte (hPSC-CM) transplantation to repair infarcted heart tissue, Dr. Al-attar faced a significant challenge: while immature hPSC-CMs survive freezing, they often induce...

Pressure Increase Method Marks Significant Advancement in Cryogenic Controls and Safety

Ensuring the integrity of packaging in cryogenic environments is crucial for maintaining product quality and operational safety. Recent advancements in non-destructive leak testing technology underscore significant improvements in cryogenic controls and safety by emphasizing the need for precise and reliable testing methods. Effective leak detection is essential for preserving the...

Tests Show High Temperature Superconducting Magnets Ready for Fusion

In the early hours of September 5, 2021, engineers at MIT’s Plasma Science and Fusion Center (PSFC) achieved a groundbreaking milestone by demonstrating a world-record magnetic field strength of 20 tesla with a new high-temperature superconducting magnet. This breakthrough is crucial for advancing fusion power technology, with the potential to...

Thermionics Laboratory Empowers Precision Nanofabrication, Ultrahigh Vacuum Manipulator for Glancing Low Angle Deposition

What does a leading optics manufacturer do when striving to develop cutting-edge lenses for high-resolution imaging systems? Their quest for flawless optical performance hinges on achieving nanostructured surfaces that minimize light scattering and maximize transmission efficiency. In the intricate world of advanced materials and nanotechnology, achieving precise fabrication techniques is...

What Is the Temperature of Space?

One of the most common questions from students when presented with an introduction to in-space applications of cryogenics is “What temperature is space?” While the askers of this question are usually enthusiastically interested, thinking space to have tactile temperatures just like the playground outside the school, this is actually a...

Beckman Institute Labs Bridge Advanced Imaging and Alzheimer’s Research

The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign has embarked on a life-changing research project to advance the early detection and diagnosis of Alzheimer’s disease. With the support of a $3 million grant from the US National Institute on Aging of the National Institutes...

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Mixed Refrigerant Cycles

Most cryogenic refrigeration systems, both large scale systems and cryocoolers, use helium as a working fluid. There are a number of advantages to helium, not the least of which is that helium remains a fluid down to the lowest achievable temperatures. In order to freeze helium, pressures of over 20...

Fountain Pumps and He II Phase Separators

Helium II (He II), the second liquid phase of the 4He isotope described in this column in Cold Facts Spring 2010 (http://2csa.us/he2), can be modeled as consisting of two interpenetrating fluids. One, the superfluid component, has zero viscosity and entropy and the other, the normal fluid component, has nonzero viscosity...

Turboexpanders

A vital technology in the refrigerators and liquefiers described in Cold Facts Volume 31 Number 3 is that of turboexpanders. These devices are rotating machines in which the process fluid (e.g., helium) does work against the turboexpander while moving from high pressure to a lower pressure and thus is cooled....

Magnetic Levitation

From http://www.superconductors.org. Magnetic-levitation is an application where superconductors perform extremely well. Transport vehicles such as trains can be made to “float” on strong superconducting magnets, virtually eliminating friction between the train and its tracks. Not only would conventional electromagnets waste much of the electrical energy as heat, they would have...

Superconductivity

From Superpower website. History of Superconductivity Superconductivity was discovered in 1911 by the Dutch physicist, Heike Kammerlingh Onnes when he was able to liquefy helium by cooling it to 4 Kelvin, or -452°F. This enabled him to cool other materials close to absolute zero and investigate their electrical properties. He...

Medical Applications of Cryogenics

Neutron Therapy Cryogenics is at the heart of nuclear accelerators. Accelerators such as Fermilab’s Tevatron make neutron therapy for cancer possible. From Fermilab Today 4/20/09: Fermilab currently offers neutron therapy. But staff at Fermilab designed and built the proton accelerator used by the nation’s first hospital-based treatment center to use...

Nuclear Physics

Al Zeller National Superconducting Cyclotron Lab (NSCL) at Michigan State University zeller@nscl.msu.edu Cryogenics has a long history in nuclear physics. The technology has its origins in the use of cold traps for maintaining a vacuum, which is required to prevent beam loss and for generating high voltages used in acceleration....

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...