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High-Resolution Cryo-EM Starts Focusing on Accessibility

Structure-based designs are integral to advancing drug discovery, and in this regard, cryogenic electron microscopy (cryo-EM) has emerged as a pivotal tool for achieving high-resolution structures of proteins and protein complexes. Particularly noteworthy is its utility in elucidating the structures of protein classes that have historically resisted crystallization. Cryo-EM’s pivotal...

Cryogenic Etch Re-Emerges

Cryogenic etch, sometimes called cryo etch, is one of two ways to enable deep silicon or high-aspect ratio (HAR) etches in devices, where the features are long, narrow and deep. The other and most popular method is the two-step Bosch process, where you etch out a part of the structure...

Tokamak Energy’s Fusion Magnet System Passes Cryogenic Tests

UK-based Tokamak Energy’s superconducting magnet system, which is being built to replicate fusion energy power plant forces, has passed significant milestone cryogenic tests. Creating fusion energy requires strong magnetic fields to confine and control the extremely hot hydrogen fuel, which becomes a plasma several times hotter than the center of...

RegO Adds Pressure Regulators for Cryogenic Vessels

RegO Products has unveiled its latest breakthrough: the CBE504 Series of Half-Inch Pressure Builder-Economizer Regulators. Designed to enhance cryogenic vessel operations, these regulators prioritize pressure control and product preservation. The CBE504 Series boasts numerous improvements over the previous CB504 model, including a more compact form factor and a broader range...

Ziath Preserves the Future, One Sample at a Time

In the realm of scientific discovery, the value of biological specimens cannot be overstated. They serve as essential windows into understanding life’s intricate mysteries. From the smallest molecules to the most complex organisms, researchers strive to unlock the secrets held within these samples. To safeguard these invaluable assets, a pioneering...

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Space Cryogenics

Space cryogenics is, somewhat obviously, the application of cryogenics to space exploration and science. The use of cryogenics in space optimizes the launching of vehicles, provides power and life support to spacecraft and is critical for many scientific observations.Space cryogenics has a number of challenges and has driven both pure...

Exergy

The science of thermodynamics plays a major role in cryogenics. It underlies the various refrigeration cycles, from Carnot to Brayton (Cold Facts Vol. 32 No. 2) and Joule-Thomson, is a fundamental part of the definition of terms such as coefficient of performance (Cold Facts Vol. 31 No. 1) and even...

Cryogenic Treatment

Cryogenic treatment is the process of cooling materials to cryogenic temperatures temporarily to improve their material properties at room temperature. This is distinct from cooling materials down to cryogenic temperatures to take advantage of phenomena such as superconductivity that only occur at cryogenic temperatures. Cryogenic treatment, sometimes also referred to...

Magnetic Levitation

From http://www.superconductors.org. Magnetic-levitation is an application where superconductors perform extremely well. Transport vehicles such as trains can be made to “float” on strong superconducting magnets, virtually eliminating friction between the train and its tracks. Not only would conventional electromagnets waste much of the electrical energy as heat, they would have...

Superconductivity

From Superpower website. History of Superconductivity Superconductivity was discovered in 1911 by the Dutch physicist, Heike Kammerlingh Onnes when he was able to liquefy helium by cooling it to 4 Kelvin, or -452°F. This enabled him to cool other materials close to absolute zero and investigate their electrical properties. He...

Medical Applications of Cryogenics

Neutron Therapy Cryogenics is at the heart of nuclear accelerators. Accelerators such as Fermilab’s Tevatron make neutron therapy for cancer possible. From Fermilab Today 4/20/09: Fermilab currently offers neutron therapy. But staff at Fermilab designed and built the proton accelerator used by the nation’s first hospital-based treatment center to use...

Nuclear Physics

Al Zeller National Superconducting Cyclotron Lab (NSCL) at Michigan State University zeller@nscl.msu.edu Cryogenics has a long history in nuclear physics. The technology has its origins in the use of cold traps for maintaining a vacuum, which is required to prevent beam loss and for generating high voltages used in acceleration....

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...