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New Microscope Advances Cryo-ET Research

Thermo Fisher Scientific Inc. unveiled the Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (Cryo-PFIB), a new connected and automated microscope designed to advance the pace of cryo-electron tomography (cryo-ET) research. Cryo-ET makes it possible to study how proteins and other molecules operate together in a cellular context, at resolutions unsurpassed by...

Excavation of Huge Caverns for DUNE Particle Detector Underway

Around a mile below the surface in South Dakota, construction crews are hard at work excavating around 1,000 tons of rock per day. Their goal is to make room for a large underground facility that will house an international effort aimed at studying neutrinos—highly elusive subatomic particles that may hold...

In DNA–Scientists find solution to building superconductor that could transform technology

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.  One possible outcome of such engineered materials could be superconductors, which have zero electrical resistance, allowing electrons to flow unimpeded. That means...

Researchers Take First-Ever Cryo-EM Images of Nitrogenase in Action

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action. Now, for the first time, researchers at the University of California San Diego report near-atomic-resolution snapshots of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM). The...

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Dewar

A dewar is a type of cryostat named after Sir James Dewar, the researcher who first developed the concept of a vacuum insulated container with silvered walls to reflect thermal radiation. Dewar was the first to liquefy hydrogen, and he created the device to store his discovery. The thermos bottle...

Stirling and Gifford-McMahon Cryocoolers

Stirling and Gifford-McMahon (GM) cryocoolers are two of the most commonly used cryocoolers in cryogenics. Both devices have a significant industrial base and operate at a wide range of temperatures and capacities. The thermodynamic cycles for both of these cryocoolers are quite similar. The Stirling cycle consists of a compressor,...

Liquefied Natural Gas (LNG)

A significant commercial application of cryogenics is the liquefaction, transport and storage of natural gas. Liquefied Natural Gas (LNG) is generally 95 percent methane with a few percent ethane and much lower concentrations of propane and butane. LNG liquefies at 111.6 K. Unlike many applications of cryogenics, the motivation for...

History of Cryogenics

From the Fall 1999 issue of Cold Facts magazine Millennium Breakthroughs A variety of CSA members give different perspectives on the past millennium: What were the most significant breakthroughs in cryogenics during the past millennium? Prof. R.G. Scurlock, Kryos Technology, scurlock@soton.ac.uk (“Breakthrough” = way through obstacles — Oxford English Dictionary)...

Cryobiology

Andreas Sputtek Past President Society for Cryobiology sputtek@uke.uni-hamburg.de or http://www.sputtek.de/. The word cryobiology (from the Greek words “cryo” = cold, “bios” = life, and “logos” = science) literally signifies the science of life at low temperatures. In practice, this field comprises the study of any biological material or system (e.g.,...

Cryogenic Insulation

James E. Fesmire Cryogenics Test Laboratory NASA Kennedy Space Center james.e.fesmire@nasa.gov Introduction In today’s world, the use of cryogenics and low-temperature refrigeration is taking a more and more significant role. From the food industry, transportation, energy, and medical applications to the Space Shuttle, cryogenic liquids must be stored, handled, and...

Cryogenic Treatment of Materials

F.J. Diekman Controlled Thermal Processing, Inc. info@metal-wear.com Cryogenic Processing (also called cryogenic treatment, and incorrectly “cryogenic tempering”) is a process that uses cryogenic temperatures to modify materials to enhance their performance. Cryogenic Processing involves the slow reduction in temperature of the material to at least -300°F (-185°C) and holding the...

In search of a calculation for designing a cryostat

I am a final year physics student at the University of Birmingham, and as part of a group I am currently designing a cryostat. One of the calculations I need to make (very soon!) is how much heat will be conducted down the walls. All information I have found so...

Safety of ethylene glycol and pressurized oxygen

We are reviewing the product design of liquid filled differential level gauges and want to insure that they meet the industry requirements. The former license owner had authorized that a fill fluid of ethylene glycol (68%) and distilled water (32%) could be used for oxygen service up to 500 psi....