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Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Cryogenic Technique Reveals Fraudulent Food and Drugs

Engineers from the University of California, Riverside have developed "chronoprinting," a new technique that can detect fake drugs and food using videos recorded while samples undergo alterations. The technology requires only a few relatively inexpensive pieces of equipment, free software to accurately distinguish pure from inferior food or medicine and...

NASA’s JPL Seeking Applicants for First Space Accelerator

NASA's first aerospace accelerator program will select 10 startup companies to take part in a three-month pilot program to develop new technologies for space. Applications will be accepted through April 7. Selected teams will develop concepts and business plans over a three-month period and then pitch their results to the...

TRIUMF Receives Historic Canadian Investment

The Government of Canada has announced a five year and $292.7M investment supporting laboratory operations at TRIUMF (CSA CSM). The donation comes in response to TRIUMF's recently published Five-Year Plan 2020-2025 and represents the country's largest single investment there to date.

Latest in Defining Cryogenics

Cold Compressors

A common way to provide cooling below the normal boiling point of helium (4.2K) is to reduce the pressure above the bath of liquid helium, thus also reducing the bath’s equilibrium saturation temperature. For example, to produce a 1.8K bath of liquid helium, the saturation pressure has to be reduced...

Kapitza Conductance

Kapitza conductance refers to the heat transfer between a solid surface and a fluid that covers that surface. Fundamentally, it describes the inherent difficulty in transferring energy from a solid to the fluid covering the solid surface. This phenomenon was first observed by P. L. Kapitza in 1941 while studying...

Thermosyphons

A thermosyphon (or thermosiphon) is a device that transfers heat via natural convection in a fluid. The natural convection is driven by gravity with the colder, denser fluid flowing downhill and the warmer, less dense fluid flowing back up. Thus, thermosyphons connect an object to be cooled with a reservoir...

Latest in Cryo Central

History of Cryogenics

From the Fall 1999 issue of Cold Facts magazine Millennium Breakthroughs A variety of CSA members give different perspectives on the past millennium: What were the most significant breakthroughs in cryogenics during the past millennium? Prof. R.G. Scurlock, Kryos Technology, scurlock@soton.ac.uk (“Breakthrough” = way through obstacles — Oxford English Dictionary)...

Cryobiology

Andreas Sputtek Past President Society for Cryobiology sputtek@uke.uni-hamburg.de or http://www.sputtek.de/. The word cryobiology (from the Greek words “cryo” = cold, “bios” = life, and “logos” = science) literally signifies the science of life at low temperatures. In practice, this field comprises the study of any biological material or system (e.g.,...

Cryogenic Insulation

James E. Fesmire Cryogenics Test Laboratory NASA Kennedy Space Center james.e.fesmire@nasa.gov Introduction In today’s world, the use of cryogenics and low-temperature refrigeration is taking a more and more significant role. From the food industry, transportation, energy, and medical applications to the Space Shuttle, cryogenic liquids must be stored, handled, and...

Cryogenic Treatment of Materials

F.J. Diekman Controlled Thermal Processing, Inc. info@metal-wear.com Cryogenic Processing (also called cryogenic treatment, and incorrectly “cryogenic tempering”) is a process that uses cryogenic temperatures to modify materials to enhance their performance. Cryogenic Processing involves the slow reduction in temperature of the material to at least -300°F (-185°C) and holding the...

Latest in Ask the Experts

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...

Separated layers of ice over a pipe

I want to know that why there are different layers of ice over a pipe carrying a cryogenic fluid, each layer separated with clear marks / lines? What do these layers signify?

Using nitrogen as a cryogen

Is it possible to achieve -200˚C using nitrogen as a cryogen?

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