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New Approach for the Identification of Metabolites Using LC with Ion Mobility and Cryogenic Spectroscopy

Researchers from Polytechnique Fédérale de Lausanne in Switzerland have developed a new approach for identifying isomeric and isobaric metabolites using high-resolution ion mobility spectrometry (IMS) and cryogenic infrared (IR) spectroscopy. The complex structure of metabolites has made their identification challenging, and analytical standards are often required to confirm their presence...

Consortium Develops Cryogenic 4 K and 77 K Transistor Models

The Innovate UK-funded CryoCMOS Consortium, led by SureCore Ltd, reports that it has successfully created new, PDK-quality, transistor models characterized for both 4 K and 77 K cryogenic operation. SureCore is using these to develop key foundation IP to enable the design of cryo-control ASICs for use in the quantum...

4 Ways Cryogenic Applications of Helium Can Be Used

Helium is a gas with properties that make it useful for many different purposes, from cooling to providing lift in airships. By understanding the basics of its cryogenic principles, we can understand how this gas works and its various uses. The aspects of cryogenic science emerged in early 19th-century experiments by Faraday...

NASA’s Quantum Detector Achieves World- Leading Milestone

A new JPL- and Caltech-developed detector could transform how quantum computers located thousands of miles apart exchange huge quantities of quantum data. Quantum computers hold the promise of operating millions of times faster than conventional computers. But to communicate over long distances, quantum computers will need a dedicated quantum communications...

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Mixed Refrigerant Cycles

Most cryogenic refrigeration systems, both large scale systems and cryocoolers, use helium as a working fluid. There are a number of advantages to helium, not the least of which is that helium remains a fluid down to the lowest achievable temperatures. In order to freeze helium, pressures of over 20...

Fountain Pumps and He II Phase Separators

Helium II (He II), the second liquid phase of the 4He isotope described in this column in Cold Facts Spring 2010 (http://2csa.us/he2), can be modeled as consisting of two interpenetrating fluids. One, the superfluid component, has zero viscosity and entropy and the other, the normal fluid component, has nonzero viscosity...

Turboexpanders

A vital technology in the refrigerators and liquefiers described in Cold Facts Volume 31 Number 3 is that of turboexpanders. These devices are rotating machines in which the process fluid (e.g., helium) does work against the turboexpander while moving from high pressure to a lower pressure and thus is cooled....

Cryogenics in Space

Peter Kittel University of California-Berkeley pkittel@cal.berkeley.edu Space Cryogenics is the application of cryogenics to space missions. These applications fall into two broad areas, supporting space science missions and supporting the space transportation infrastructure. Science applications: The atmosphere is opaque to much of the electro-magnetic spectrum. In space, the absence of...

Cryosurgery

Review of Cryosurgery Boris Rubinsky, PhD Hebrew University School of Science and Engineering Research Center for Biomedical Engineering 78b Ross Building Givat Ram, Jerusalem 91904 Israel rubinsky@cs.huji.ac.il as published in Annual Review of Biomedical Engineering, August 2000, Vol. 2, pp. 157-187. Abstract: Cryosurgery is a surgical technique that employs freezing...

Liquefied Natural Gas

Liquefied Natural Gas as it relates to the Field of Cryogenics John W. Bonn VJ Systems, LLC johnbonn@vjsystems-lic.com Today the world is looking for a cleaner fuel and Liquefied Natural Gas (LNG) plays a large part in achieving this goal. LNG in a liquid form is at -162°C (-259°F) and...

Food Processing

Cryogenics and Food The industrial gas industry provides a host of products and services related to food. The various gases have useful and sometimes fascinating applications in food industry. “The food industry is not a homogenous industry. The needs of customers processing hamburger vs. poultry vs. strawberries vs. seafood, for...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...