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Cryo-EM Reveals Crucial Electrical Switch in Brain

Scientists using cryo-EM have revealed the structure of a critical receptor (AMPA) in the brain associated with learning, memory, behavior and mood. The research was also the first to reveal the structure of AMPA receptors in a natural state, a discovery that could lead to new insight about the mechanism...

Researchers Discover Water that Never Freezes

Can water reach -263°C without turning into ice? The answer is yes, according to a group of physicists and chemists from ETH Zurich and the University of Zurich who identified an unusual way to not only prevent water from forming ice crystals while at extreme sub-zero temperatures but to also...

Working Together as a “virtual telescope,” Observatories Around the World Produce First Direct Images of a Black Hole

MIT News reported on April 10 that an international team of over 200 astronomers had captured the first direct images of a black hole. They accomplished this remarkable feat by coordinating the power of nine major radio observatories on four continents, to work together as a virtual, Earth-sized telescope. In...

Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Latest in Defining Cryogenics

Dewar

A dewar is a type of cryostat named after Sir James Dewar, the researcher who first developed the concept of a vacuum insulated container with silvered walls to reflect thermal radiation. Dewar was the first to liquefy hydrogen, and he created the device to store his discovery. The thermos bottle...

Stirling and Gifford-McMahon Cryocoolers

Stirling and Gifford-McMahon (GM) cryocoolers are two of the most commonly used cryocoolers in cryogenics. Both devices have a significant industrial base and operate at a wide range of temperatures and capacities. The thermodynamic cycles for both of these cryocoolers are quite similar. The Stirling cycle consists of a compressor,...

Liquefied Natural Gas (LNG)

A significant commercial application of cryogenics is the liquefaction, transport and storage of natural gas. Liquefied Natural Gas (LNG) is generally 95 percent methane with a few percent ethane and much lower concentrations of propane and butane. LNG liquefies at 111.6 K. Unlike many applications of cryogenics, the motivation for...

Latest in Cryo Central

Magnets

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. Particle physics uses accelerators to recreate the conditions of the early universe in an attempt to piece together the complex puzzle of how we got to where we are today. These huge machines are used...

Energy Storage

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. With power lines increasingly congested and prone to instability, strategic injection of brief bursts of real power can play a crucial role in maintaining grid reliability. Small-scale Superconducting Magnetic Energy Storage (SMES) systems, based on...

Astronomy

ASTRONOMY IN SPACE by Peter V. Mason, retired, Jet Propulsion Laboratory, and Visiting Associate, California Institute of Technology. Pmason@alumni.caltech.edu In thinking about the reasons to perform astronomy in space, we first consider the effect of the earth’s atmosphere. On a scale of decreasing energy, gamma rays, cosmic rays, X-rays and...

Cryocoolers

What is a Cryocooler? A mechanism that can extract heat from an object (cooler) and by doing so draw its temperature down below approximately 150 Kelvin (cryo). — (Courtesy Dr. Willy Gully) What is the difference between a Cryocooler and a Cryostat? A cryostat is any device designed to maintain...

Latest in Ask the Experts

Power usage: cryogenic systems vs. regular refrigerators

A recent project highlighted to me that closed cycle cryogenic cooling systems use far more electrical power to reduce temperatures by a few watts than regular refrigerators. I am sure it must be something to do with the extra difficulty of removing the heat from the liquid nitrogen or similar...

Redundancy strategies for mechanical -80C freezers

I was wondering what kind of redundancy strategies are people using for their mechanical -80C freezers? I am aware of the following. Please add if you are doing something different. 1) 1 Backup freezer for every 10 freezers – Empty and maintained at -80C at all times 2) Backup C02...

Safety guidelines for handling cryo vessels of nitrogen

I am looking for any safety guidelines for handling cryogenic vessels of nitrogen indoors and outdoors. I am especially interested in recommendations for area monitors to detect leaks, flow detection devices, etc.

Method to move components in a cryogenic environment

Does anyone know of a method with which to reliably move components in a cryogenic environment? We are interested in moving detectors in a cryogenically cooled (2K) vacuum chamber, which is contained within a larger cryostat/isolation vacuum with thermal shields. As the desired horizontal or vertical displacement is between 10...

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