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Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Cryogenic Technique Reveals Fraudulent Food and Drugs

Engineers from the University of California, Riverside have developed "chronoprinting," a new technique that can detect fake drugs and food using videos recorded while samples undergo alterations. The technology requires only a few relatively inexpensive pieces of equipment, free software to accurately distinguish pure from inferior food or medicine and...

NASA’s JPL Seeking Applicants for First Space Accelerator

NASA's first aerospace accelerator program will select 10 startup companies to take part in a three-month pilot program to develop new technologies for space. Applications will be accepted through April 7. Selected teams will develop concepts and business plans over a three-month period and then pitch their results to the...

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Refrigerators and Liquefiers

Two of the most common terms used in cryogenics are “refrigerator” and “liquefier.” These terms describe similar and, as will be seen, in some cases identical components. A refrigerator provides cooling (that is, absorbs heat) at cryogenic temperatures. Refrigerators typically put a working fluid (such as helium) through one of...

Air Separation

Air separation is one of the largest, as well as earliest, industrial applications of cryogenics. In this process, cryogenic temperatures are used to separate air into its constituent gases: nitrogen (78.08%), oxygen (20.95%), argon (0.93%) and carbon dioxide (0.3%). Trace gases such as krypton, neon, xenon and helium total far...

Coefficient of Performance and Figure of Merit

The coefficient of performance (COP) is used to describe the effectiveness of refrigerators, including those operating at cryogenic temperatures. The COP is defined as the amount of heat removed at the cryogenic operating temperature of the refrigerator divided by the amount of work that must be applied to remove the...

Primary Standards

Elie K. Track Hypres, Inc. elie@hypres.com http://www.hypres.com/ Primary standards involve the exact definition and realization of units of measurement for various quantities, time, length, mass, voltage, resistance, current, etc. International agreements based on the latest scientific knowledge define those units, and their realizations vary depending on the unit itself. For...

Shrink Fitting

Robin A. Rhodes Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Shrink fitting, (or “compression fitting” as it is sometimes called), is a method used to insert a pin or bushing into a housing or other assembly requiring an extremely tight tolerance fit. It can be used as an alternative to...

Telecommunications

From the Winter 2004 issue of Cold Facts magazine The recent M-Calc IV — 4th Industry Assessment workshop discussing military and commercial applications for low-cost cryocoolers, held in November in San Diego, highlighted progress being made in cryogenics as applied in telecommunications. The reliability and long lifetime of projects now...

Wind Tunnels

Dr. Robert Kilgore The development of the cryogenic wind tunnel is one of many significant breakthroughs in both cryogenics and wind-tunnel technology made during the past millennium. Interest in the development of high-speed commercial and military aircraft resulted in a review of problems of flow simulation in transonic wind tunnels...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...