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Technifab Hoses
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Designing Cryogenic Piping Systems for the Demands of Modern Life Science Labs

As life science facilities become more advanced and specialized, the infrastructure behind them must evolve to meet increasing demands for efficiency, precision, and cost-effectiveness. Technifab Products, Inc., in partnership with CryoWorks, is leading the way in cryogenic piping solutions for the biotech, pharmaceutical, and research sectors—supporting applications ranging from cryosurgery...
July 9, 2025
Quantum Design
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Quantum Design Signs Agreement to Acquire NanoScience Division ofOxford Instruments

Quantum Design, a leading developer of cryogenic measurement systems based in San Diego, California, has announced a definitive agreement to acquire the NanoScience Division of Oxford Instruments. Located in Oxfordshire, United Kingdom, NanoScience is a global innovator in ultra-low-temperature cryogenic instrumentation. The acquisition, expected to close by the end of...
July 9, 2025
A Soyuz rocket launches to the International Space Station with Expedition 73 crew members including NASA astronaut Jonny Kim on Tuesday, April 8, 2025, at the Baikonur Cosmodrome in Kazakhstan. Photo ©NASA/Joel Kowsky
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Stainless VJP Enable Cryogenic Liquid Supply Chains in Space and on Earth

A Soyuz rocket launches to the International Space Station with Expedition 73 crew members including NASA astronaut Jonny Kim on Tuesday, April 8, 2025, at the Baikonur Cosmodrome in Kazakhstan. Photo ©NASA/Joel Kowsky What do space exploration and the Hydrogen Economy have in common? A need to transport large volumes...
July 9, 2025
News

Google and Commonwealth Fusion Systems Sign Strategic Partnership

Credit: Commonwealth Fusion Systems Google and Commonwealth Fusion Systems (CFS) today announced a new global milestone, a bold partnership to develop, deploy and scale clean, secure fusion power. Google signed a power purchase agreement (PPA) for 200 megawatts (MW) of electricity from CFS’ inaugural ARC power plant, which CFS expects...
June 30, 2025
Image source: Taihan/SuperNode
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Korean Cable Corp Signs Deal Next-Gen Superconductors

Image source: Taihan/SuperNodeA leading Korean cable company has signed a deal with an Irish firm to develop “next-generation” superconducting cables for the offshore wind industry. Taihan will work with Dublin-based SuperNode on the design and roll out of polymer-based transmission cables which promise to “significantly” enhance efficiency and simplify installation...
June 24, 2025
Modifying gas chromatography systems with cryogenic technologies Subscribe for newsletter updates Researchers at Monash University in Clayton, Australia, have developed a new 3D-printed device for gas chromatography (GC), demonstrating its effectiveness in carrying out multidimensional and enantioselective separations. GC has long been central to chemical analysis, particularly for mixtures of volatile compounds. However, its resolution can be insufficient for separating complex mixtures. Scientists have addressed this limitation with techniques such as multidimensional gas chromatography (MDGC) and comprehensive two-dimensional gas chromatography (GC × GC), which both require modulation devices. Thermal modulators, among the earliest developed, remain widely used. In this study, the researchers designed a stainless steel 3D-printed device to function as a cold trapping assembly when cooled with liquid CO₂. Its operational principle mirrors that of a longitudinally modulated cryogenic system (LMCS). Cryogenic technologies have precedent in chromatography, offering the capacity to remobilise trapped components, thereby enabling new analytical approaches. When integrated with GC, such devices allow analysts to apply advanced separation techniques. The team detailed the enclosure design and assessed its performance for collecting and rapidly remobilising volatile organic compounds (VOCs). Modulation period precision was evaluated, yielding a maximum error of 8 microseconds and an average variation of less than 1 nanosecond across 10,000 successive modulations. Using a C5–C9 alkane series, the system was shown to effectively trap analytes, with peaks achieving a full width at half height (FWHH) as low as 65 milliseconds. The maximum trapping time was determined using hexane, with the modulator retaining the compound for up to 9 seconds at 100 °C before breakthroughs occurred. The system was also used to investigate the enantioselective separation of limonene, a compound derived from citrus peel oils. Although only one chiral column was used, different column lengths (ranging from 20 cm to 5.0 m) were drawn through the modulator. These effectively acted as enantioselective second-dimension (2D) columns. Injected (R,S)-limonene enantiomers were collected simultaneously and then rapidly transferred to the 2D column. The 3D-printed modulator successfully trapped hexane, enabling modulation periods of up to 8 seconds. This was achieved at oven temperatures of up to 100 °C. While higher temperatures were not tested, the researchers suggest that hexane modulation beyond this point is likely feasible. Ultimately, the study demonstrated the feasibility of comprehensive two-dimensional GC using 3D-printed modulators with a tea tree oil sample. Although 2D retention times exceeded optimal limits for GC × GC under the conditions tested, the authors propose that further refinement of columns and methods could yield improved separation.
News

Modifying Gas Chromatography Systems with Cryogenic Technologies

Clayton Campus, Melbourne, Victoria. Credit: Montash University, Australia Researchers at Monash University in Clayton, Australia, have developed a new 3D-printed device for gas chromatography (GC), demonstrating its effectiveness in carrying out multidimensional and enantioselective separations. GC has long been central to chemical analysis, particularly for mixtures of volatile compounds. However,...
June 24, 2025

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Latest in Defining Cryogenics
Defining Cryogenics

Stability

Stability refers to the ability of a device employing superconductors to remain in its superconducting state after part of the superconductor transitions back to its normal conducting state due to a disturbance. While the concept can apply to many superconducting devices—transmission lines, generators, motors, etc.—it is most commonly considered in...
March 6, 2018
Defining Cryogenics

Cable-in-Conduit Conductors

Cable-in-Conduit Conductors (CICC) are a common form of superconducting cable used in large-scale applications. There are several varieties of CICCs, but they all consist of many small, stabilized superconducting wires contained within a conduit through which a coolant (typically supercritical He II) flows. Figure 1 shows the cross section of...
November 2, 2017
Defining Cryogenics

Bayonet Coupling

A bayonet coupling is a demountable joint that allows for quick and easy connection and disconnection of cryogenic components, including transfer lines, cryostats, liquefiers and refrigerators. Bayonets provide a number of advantages, chief among them the ability to connect and disconnect the bayonets while components they connect are still at...
September 18, 2017
Latest in Cryo Central
Cryo Central

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...
May 29, 2020
Cryo Central

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...
August 10, 2010
Cryo Central

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...
June 18, 2010
Cryo Central

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...
May 28, 2010
Latest in Ask the Experts
Ask the Experts

Power usage: cryogenic systems vs. regular refrigerators

A recent project highlighted to me that closed cycle cryogenic cooling systems use far more electrical power to reduce temperatures by a few watts than regular refrigerators. I am sure it must be something to do with the extra difficulty of removing the heat from the liquid nitrogen or similar...
August 23, 2012
Ask the Experts

Redundancy strategies for mechanical -80C freezers

I was wondering what kind of redundancy strategies are people using for their mechanical -80C freezers? I am aware of the following. Please add if you are doing something different. 1) 1 Backup freezer for every 10 freezers – Empty and maintained at -80C at all times 2) Backup C02...
August 23, 2012
Ask the Experts

Method to move components in a cryogenic environment

Does anyone know of a method with which to reliably move components in a cryogenic environment? We are interested in moving detectors in a cryogenically cooled (2K) vacuum chamber, which is contained within a larger cryostat/isolation vacuum with thermal shields. As the desired horizontal or vertical displacement is between 10...
August 23, 2012