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IIT Kanpur Researchers Unravel Key Drug Target Receptor for Cancer and Respiratory Disease Treatments

A team of researchers from the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology, Kanpur, have successfully visualized the atomic structure of CXCR2, a key human receptor involved in cancer progression and respiratory disorders. This discovery, published in the prestigious journal Molecular Cell, paves the way for...

Vacuum pumps like never before… in LEGO® Form!

Vacuum technology is essential to the modern world—especially for fields like cryogenics, semiconductor manufacturing, pharmaceuticals, and environmental engineering. Yet for all their significance, vacuum pumps are rarely seen outside of labs and industrial settings. Now, Leybold is taking a novel approach to spotlighting these critical machines—by turning them into LEGO®...

Jefferson Lab Dedicates Niobium-Tin Particle Accelerator Prototype

More than 30 of the world’s most advanced particle accelerators rely on one technology: superconducting radio-frequency (SRF). This technology, typically powered by pure niobium metal, has seen recent advancements with the introduction of niobium-tin alloys, which promise greater efficiency. The US Department of Energy’s (DOE) Thomas Jefferson National Accelerator Facility...

Vacuum Barrier Corporation Enhances Customer Support Through Field Service Evolution

Vacuum Barrier Corporation (VBC) has long been recognized for its commitment to excellence in cryogenic systems and liquid nitrogen (LN2) solutions. Recently, the company has made significant strides in bolstering its customer support by establishing a dedicated department for reliability and technical support. Dana Muse, Reliability and Technical Support Manager,...

Argonne Empowers Female Energy Leaders

Argonne National Laboratory (CSA CSM) recently hosted 12 women leaders from Net Zero World partner countries for a two-week training program under the Climate Smart Women Energy Leaders (CSWEL) initiative. In collaboration with the U.S. Department of Energy’s (DOE) Net Zero World Initiative, the program aimed to equip participants with...

Honoring This Year’s Women in Cryo 2025

The Cryogenic Society of America and Cold Facts celebrates distinguished women who embody the expertise and drive that is putting cryogenics and superconductivity at the forefront of energy, aerospace, quantum, and myriad other fields of industry. Congratulations! Iqra Azam Vera Hansper Jennifer Hennis Tamanna Joshi Nora Juhasz Susan Magi Kayla Rajsky Tara...

Latest in Defining Cryogenics

Joule-Thomson Effect

The Joule-Thomson (JT) effect is a thermodynamic process that occurs when a fluid expands from high pressure to low pressure at constant enthalpy (an isenthalpic process). Such a process can be approximated in the real world by expanding a fluid from high pressure to low pressure across a valve. Under...

Current Leads

One of the challenges of using superconducting magnets is the connection of the magnet to a room temperature power supply. This is accomplished via current leads. The trick is that current leads should ideally have a low heat leak, since they connect room temperature to cryogenic temperature, while at the...

Multilayer Insulation

Multilayer insulation (also referred to as superinsulation) is a key component in the reduction of heat leak to cryogenic systems due to thermal radiation. MLI consists of a series of uncooled reflective surfaces placed in the vacuum space between two surfaces, one warmer than the other. Generally speaking, for ideal...

Latest in Cryo Central

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Latest in Ask the Experts

Power usage: cryogenic systems vs. regular refrigerators

A recent project highlighted to me that closed cycle cryogenic cooling systems use far more electrical power to reduce temperatures by a few watts than regular refrigerators. I am sure it must be something to do with the extra difficulty of removing the heat from the liquid nitrogen or similar...

Redundancy strategies for mechanical -80C freezers

I was wondering what kind of redundancy strategies are people using for their mechanical -80C freezers? I am aware of the following. Please add if you are doing something different. 1) 1 Backup freezer for every 10 freezers – Empty and maintained at -80C at all times 2) Backup C02...

Safety guidelines for handling cryo vessels of nitrogen

I am looking for any safety guidelines for handling cryogenic vessels of nitrogen indoors and outdoors. I am especially interested in recommendations for area monitors to detect leaks, flow detection devices, etc.

Method to move components in a cryogenic environment

Does anyone know of a method with which to reliably move components in a cryogenic environment? We are interested in moving detectors in a cryogenically cooled (2K) vacuum chamber, which is contained within a larger cryostat/isolation vacuum with thermal shields. As the desired horizontal or vertical displacement is between 10...

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