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High-Resolution Cryo-EM Starts Focusing on Accessibility

Structure-based designs are integral to advancing drug discovery, and in this regard, cryogenic electron microscopy (cryo-EM) has emerged as a pivotal tool for achieving high-resolution structures of proteins and protein complexes. Particularly noteworthy is its utility in elucidating the structures of protein classes that have historically resisted crystallization. Cryo-EM’s pivotal...

Cryogenic Etch Re-Emerges

Cryogenic etch, sometimes called cryo etch, is one of two ways to enable deep silicon or high-aspect ratio (HAR) etches in devices, where the features are long, narrow and deep. The other and most popular method is the two-step Bosch process, where you etch out a part of the structure...

Tokamak Energy’s Fusion Magnet System Passes Cryogenic Tests

UK-based Tokamak Energy’s superconducting magnet system, which is being built to replicate fusion energy power plant forces, has passed significant milestone cryogenic tests. Creating fusion energy requires strong magnetic fields to confine and control the extremely hot hydrogen fuel, which becomes a plasma several times hotter than the center of...

RegO Adds Pressure Regulators for Cryogenic Vessels

RegO Products has unveiled its latest breakthrough: the CBE504 Series of Half-Inch Pressure Builder-Economizer Regulators. Designed to enhance cryogenic vessel operations, these regulators prioritize pressure control and product preservation. The CBE504 Series boasts numerous improvements over the previous CB504 model, including a more compact form factor and a broader range...

Ziath Preserves the Future, One Sample at a Time

In the realm of scientific discovery, the value of biological specimens cannot be overstated. They serve as essential windows into understanding life’s intricate mysteries. From the smallest molecules to the most complex organisms, researchers strive to unlock the secrets held within these samples. To safeguard these invaluable assets, a pioneering...

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Dewar

A dewar is a type of cryostat named after Sir James Dewar, the researcher who first developed the concept of a vacuum insulated container with silvered walls to reflect thermal radiation. Dewar was the first to liquefy hydrogen, and he created the device to store his discovery. The thermos bottle...

Stirling and Gifford-McMahon Cryocoolers

Stirling and Gifford-McMahon (GM) cryocoolers are two of the most commonly used cryocoolers in cryogenics. Both devices have a significant industrial base and operate at a wide range of temperatures and capacities. The thermodynamic cycles for both of these cryocoolers are quite similar. The Stirling cycle consists of a compressor,...

Liquefied Natural Gas (LNG)

A significant commercial application of cryogenics is the liquefaction, transport and storage of natural gas. Liquefied Natural Gas (LNG) is generally 95 percent methane with a few percent ethane and much lower concentrations of propane and butane. LNG liquefies at 111.6 K. Unlike many applications of cryogenics, the motivation for...

Magnets

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. Particle physics uses accelerators to recreate the conditions of the early universe in an attempt to piece together the complex puzzle of how we got to where we are today. These huge machines are used...

Energy Storage

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. With power lines increasingly congested and prone to instability, strategic injection of brief bursts of real power can play a crucial role in maintaining grid reliability. Small-scale Superconducting Magnetic Energy Storage (SMES) systems, based on...

Astronomy

ASTRONOMY IN SPACE by Peter V. Mason, retired,  Jet Propulsion Laboratory, and Visiting Associate, California Institute of Technology. Pmason@alumni.caltech.edu In thinking about the reasons to perform astronomy in space, we first consider the effect of the earth’s atmosphere.  On a scale of decreasing energy, gamma rays, cosmic rays, X-rays and...

Cryocoolers

What is a Cryocooler? A mechanism that can extract heat from an object (cooler) and by doing so draw its temperature down below approximately 150 Kelvin (cryo). — (Courtesy Dr. Willy Gully) What is the difference between a Cryocooler and a Cryostat? A cryostat is any device designed to maintain...

Seeking recommendations for commercial sensors

I would like to measure vibrations in small LHe cryostats. Could anybody recommend commercial sensors which would be suitable for the purpose? I am interested in the frequency range between 1Hz and a couple of KHz, with particular attention to the low frequency side.

Estimating cost of carbon steel, pure helium storage tanks

In order to perform an indicative cost assessment of our helium cryogenic plant (still in the design phase), I need an estimation of the cost of carbon steel room temperature pure helium storage tanks. The storage pressure is 20 bar. Can anyone give me suggestions about how to estimate the...

Supplier of pressure sensor that works down to 4.2 K

In an actual experiment we would like to measure the static pressure in a cryostat in the range between one and four bar. Therefore we are looking for some (more or less) cheap pressure sensors that work in liquid helium in the pressure range up to five bar. Unfortunately all...

Looking for reference/textbook suggestions

Can you suggest some reference textbooks for practical thermodynamics applications in cryogenic fields? I need textbooks with cryogenics calculations and examples, dimensioning procedures, second principle applications in cryogenics, heat load calculations, cryogenic pump application, etc. Do such books exist? Does any similar source of information exist?