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Cryo-EM Reveals Crucial Electrical Switch in Brain

Scientists using cryo-EM have revealed the structure of a critical receptor (AMPA) in the brain associated with learning, memory, behavior and mood. The research was also the first to reveal the structure of AMPA receptors in a natural state, a discovery that could lead to new insight about the mechanism...

Researchers Discover Water that Never Freezes

Can water reach -263°C without turning into ice? The answer is yes, according to a group of physicists and chemists from ETH Zurich and the University of Zurich who identified an unusual way to not only prevent water from forming ice crystals while at extreme sub-zero temperatures but to also...

Working Together as a “virtual telescope,” Observatories Around the World Produce First Direct Images of a Black Hole

MIT News reported on April 10 that an international team of over 200 astronomers had captured the first direct images of a black hole. They accomplished this remarkable feat by coordinating the power of nine major radio observatories on four continents, to work together as a virtual, Earth-sized telescope. In...

Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Latest in Defining Cryogenics

Regenerators

Regenerators or regenerative heat exchangers are a key component of cryocoolers such as pulse tube cryocoolers (Cold Facts, August 2014). Regenerator performance greatly affects the coefficient of performance of cryocoolers. Improvements in regenerator design and, in particular, regenerator materials have been an important factor in the improvement of the performance...

Pulse Tube Cryocoolers

The development of pulse tube cryocoolers has been a significant topic of research and development over the past 20 or so years. Pulse tube cryocoolers have a number of advantages over other types of cryocoolers and are now available commercially. In order to understand pulse tube cryocoolers, it’s best to...

Thermal Expansion

Thermal expansion refers to the change in size (length or volume) that a material undergoes as its temperature changes. In cryogenic systems this effect can be quite large and must be allowed for in the design. In isotropic materials, which include most engineering materials, the thermal expansion is the same...

Latest in Cryo Central

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Latest in Ask the Experts

Benefit of cryotreatment of audio circuit boards and interconnecting cables

Does cryotreatment of audio circuit boards and interconnecting cables (copper, silver, gold) properly done, provide a permanent benefit?

Standards and codes for design of cryogenic equipment?

What standards and codes are used in the design of cryogenic equipment?

Cryogenic thermophysical property data

I am in search of information regarding cryogenic thermophysical property data, specifically, Thermal Conductivity, Thermal Expansion, Stiffness and Modulus, in the 20K range. My list of materials include: Ti-6AL-4V (ELI), Al 6061-T651, and Invar (36%, plus any other composition which might have data available). Other materials which would be helpful...

Issue with insulation for ventilation system

I am with the Goodrich Corporation, an Aerospace products manufacturer. We currently utilize a number of environmental chambers (LN2 based) for environmental type conformity testing.

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