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IIT Kanpur Researchers Unravel Key Drug Target Receptor for Cancer and Respiratory Disease Treatments

A team of researchers from the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology, Kanpur, have successfully visualized the atomic structure of CXCR2, a key human receptor involved in cancer progression and respiratory disorders. This discovery, published in the prestigious journal Molecular Cell, paves the way for...

Vacuum pumps like never before… in LEGO® Form!

Vacuum technology is essential to the modern world—especially for fields like cryogenics, semiconductor manufacturing, pharmaceuticals, and environmental engineering. Yet for all their significance, vacuum pumps are rarely seen outside of labs and industrial settings. Now, Leybold is taking a novel approach to spotlighting these critical machines—by turning them into LEGO®...

Honoring This Year’s Women in Cryo 2025

The Cryogenic Society of America and Cold Facts celebrates distinguished women who embody the expertise and drive that is putting cryogenics and superconductivity at the forefront of energy, aerospace, quantum, and myriad other fields of industry. Congratulations! Iqra Azam Vera Hansper Jennifer Hennis Tamanna Joshi Nora Juhasz Susan Magi Kayla Rajsky Tara...

BS&B Safety Systems Accelerates Service to OEMs

OEMs in virtually every market, from aerospace and automotive to refrigeration and fire protection, rely on rupture disk devices for pressure relief and pressure release of gases and liquids. The challenge of time faces all product designers; how do we get a custom solution in an acceptable timeframe? Now, at least...

The Cryomech PT205: A Compact Cryocooler with a Wide Range of Applications

In today’s rapidly evolving technological landscape, the demand for efficient and compact cryocoolers is more critical than ever. A wide range of applications increasingly require high performance cooling systems that can seamlessly integrate into limited spaces. Smaller cryocoolers prove invaluable in these contexts, offering the precision and reliability necessary to...

CO2Meter’s Critical Gas Safety Solution

CO2Meter has long been recognized for its remote oxygen depletion safety alarm, which warns staff before they enter areas with dangerously low oxygen levels caused by pressurized gas leaks. Pressurizing a gas in a tank or cylinder provides a convenient way to transport and store it. Flower shops use helium cylinders...

Latest in Defining Cryogenics

Regenerators

Regenerators or regenerative heat exchangers are a key component of cryocoolers such as pulse tube cryocoolers (Cold Facts, August 2014). Regenerator performance greatly affects the coefficient of performance of cryocoolers. Improvements in regenerator design and, in particular, regenerator materials have been an important factor in the improvement of the performance...

Pulse Tube Cryocoolers

The development of pulse tube cryocoolers has been a significant topic of research and development over the past 20 or so years. Pulse tube cryocoolers have a number of advantages over other types of cryocoolers and are now available commercially. In order to understand pulse tube cryocoolers, it’s best to...

Thermal Expansion

Thermal expansion refers to the change in size (length or volume) that a material undergoes as its temperature changes. In cryogenic systems this effect can be quite large and must be allowed for in the design. In isotropic materials, which include most engineering materials, the thermal expansion is the same...

Latest in Cryo Central

Cryogenic Treatment of Materials

F.J. Diekman Controlled Thermal Processing, Inc. info@metal-wear.com Cryogenic Processing (also called cryogenic treatment, and incorrectly “cryogenic tempering”) is a process that uses cryogenic temperatures to modify materials to enhance their performance. Cryogenic Processing involves the slow reduction in temperature of the material to at least -300°F (-185°C) and holding the...

Cryogenics in Space

Peter Kittel University of California-Berkeley pkittel@cal.berkeley.edu Space Cryogenics is the application of cryogenics to space missions. These applications fall into two broad areas, supporting space science missions and supporting the space transportation infrastructure. Science applications: The atmosphere is opaque to much of the electro-magnetic spectrum. In space, the absence of...

Cryosurgery

Review of Cryosurgery Boris Rubinsky, PhD Hebrew University School of Science and Engineering Research Center for Biomedical Engineering 78b Ross Building Givat Ram, Jerusalem 91904 Israel rubinsky@cs.huji.ac.il as published in Annual Review of Biomedical Engineering, August 2000, Vol. 2, pp. 157-187. Abstract: Cryosurgery is a surgical technique that employs freezing...

Liquefied Natural Gas

Liquefied Natural Gas as it relates to the Field of Cryogenics John W. Bonn VJ Systems, LLC johnbonn@vjsystems-lic.com Today the world is looking for a cleaner fuel and Liquefied Natural Gas (LNG) plays a large part in achieving this goal. LNG in a liquid form is at -162°C (-259°F) and...

Latest in Ask the Experts

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...

Separated layers of ice over a pipe

I want to know that why there are different layers of ice over a pipe carrying a cryogenic fluid, each layer separated with clear marks / lines? What do these layers signify?

Using nitrogen as a cryogen

Is it possible to achieve -200˚C using nitrogen as a cryogen?

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