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Doctor Advances Cryopreservation in Heart Regeneration and Organ Transplantation

At Harvard Medical School and Massachusetts General Hospital, Dr. Rasha Al-attar’s research is at the forefront of advancing heart regeneration and organ transplantation. Initially focusing on stem cell-derived cardiomyocyte (hPSC-CM) transplantation to repair infarcted heart tissue, Dr. Al-attar faced a significant challenge: while immature hPSC-CMs survive freezing, they often induce...

Pressure Increase Method Marks Significant Advancement in Cryogenic Controls and Safety

Ensuring the integrity of packaging in cryogenic environments is crucial for maintaining product quality and operational safety. Recent advancements in non-destructive leak testing technology underscore significant improvements in cryogenic controls and safety by emphasizing the need for precise and reliable testing methods. Effective leak detection is essential for preserving the...

Tests Show High Temperature Superconducting Magnets Ready for Fusion

In the early hours of September 5, 2021, engineers at MIT’s Plasma Science and Fusion Center (PSFC) achieved a groundbreaking milestone by demonstrating a world-record magnetic field strength of 20 tesla with a new high-temperature superconducting magnet. This breakthrough is crucial for advancing fusion power technology, with the potential to...

Thermionics Laboratory Empowers Precision Nanofabrication, Ultrahigh Vacuum Manipulator for Glancing Low Angle Deposition

What does a leading optics manufacturer do when striving to develop cutting-edge lenses for high-resolution imaging systems? Their quest for flawless optical performance hinges on achieving nanostructured surfaces that minimize light scattering and maximize transmission efficiency. In the intricate world of advanced materials and nanotechnology, achieving precise fabrication techniques is...

What Is the Temperature of Space?

One of the most common questions from students when presented with an introduction to in-space applications of cryogenics is “What temperature is space?” While the askers of this question are usually enthusiastically interested, thinking space to have tactile temperatures just like the playground outside the school, this is actually a...

Beckman Institute Labs Bridge Advanced Imaging and Alzheimer’s Research

The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign has embarked on a life-changing research project to advance the early detection and diagnosis of Alzheimer’s disease. With the support of a $3 million grant from the US National Institute on Aging of the National Institutes...

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Dilution Refrigerators

Dilution refrigerators are a common technique for reaching temperatures below 1K, particularly where continuous cooling at these temperatures is required. Helium exists in two stable isotopes: 4He and 3He. Naturally occurring 3He is extremely rare, constituting less than 1 part per million of helium gas. However, 3He can be manufactured,...

Oxygen Deficiency Hazards

Oxygen Deficiency Hazards (ODH) are a significant safety issue in cryogenic facilities. ODH occurs when inert gases such as nitrogen, helium or argon displace room air and thus lower the percentage of oxygen in the space below that required for human life. OSHA defines an area as oxygen deficient if...

Kelvin Temperature Scale

The Kelvin temperature scale is the principal temperature scale used in cryogenics and science. The kelvin is also one of the seven base units in the Système International d’Unités (SI) and is the unit of thermodynamic temperature. Thermodynamic temperature is a fundamental physical quantity (like mass, length or electrical current)...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

In need of books to start a cryogenic engineering department

My company is going to create a cryogenic engineering department and we need some books in order to facilitate this project. This is the kind of information we would like to obtain from the books: 1- Calculations for determining the storage facilities, such as storage tanks, pumps, compressors, etc. 2-...