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What Is the Temperature of Space?

One of the most common questions from students when presented with an introduction to in-space applications of cryogenics is “What temperature is space?” While the askers of this question are usually enthusiastically interested, thinking space to have tactile temperatures just like the playground outside the school, this is actually a...

Beckman Institute Labs Bridge Advanced Imaging and Alzheimer’s Research

The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign has embarked on a life-changing research project to advance the early detection and diagnosis of Alzheimer’s disease. With the support of a $3 million grant from the US National Institute on Aging of the National Institutes...

Bluefors Lab Offers Cryo Measurements, a Low Risk Model for Experiments

Quantum technology continues to develop at a rapid pace, and the need for access to cryogenic cooling systems for quantum research has never been greater. While established institutions have an increasing number of options to choose from, startups and smaller institutions still face considerable challenges, not least of which are...

Doctor Advances Cryopreservation in Heart Regeneration and Organ Transplantation

At Harvard Medical School and Massachusetts General Hospital, Dr. Rasha Al-attar’s research is at the forefront of advancing heart regeneration and organ transplantation. Initially focusing on stem cell-derived cardiomyocyte (hPSC-CM) transplantation to repair infarcted heart tissue, Dr. Al-attar faced a significant challenge: while immature hPSC-CMs survive freezing, they often induce...

Pressure Increase Method Marks Significant Advancement in Cryogenic Controls and Safety

Ensuring the integrity of packaging in cryogenic environments is crucial for maintaining product quality and operational safety. Recent advancements in non-destructive leak testing technology underscore significant improvements in cryogenic controls and safety by emphasizing the need for precise and reliable testing methods. Effective leak detection is essential for preserving the...

Tests Show High Temperature Superconducting Magnets Ready for Fusion

In the early hours of September 5, 2021, engineers at MIT’s Plasma Science and Fusion Center (PSFC) achieved a groundbreaking milestone by demonstrating a world-record magnetic field strength of 20 tesla with a new high-temperature superconducting magnet. This breakthrough is crucial for advancing fusion power technology, with the potential to...

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Refrigerators and Liquefiers

Two of the most common terms used in cryogenics are “refrigerator” and “liquefier.” These terms describe similar and, as will be seen, in some cases identical components. A refrigerator provides cooling (that is, absorbs heat) at cryogenic temperatures. Refrigerators typically put a working fluid (such as helium) through one of...

Air Separation

Air separation is one of the largest, as well as earliest, industrial applications of cryogenics. In this process, cryogenic temperatures are used to separate air into its constituent gases: nitrogen (78.08%), oxygen (20.95%), argon (0.93%) and carbon dioxide (0.3%). Trace gases such as krypton, neon, xenon and helium total far...

Coefficient of Performance and Figure of Merit

The coefficient of performance (COP) is used to describe the effectiveness of refrigerators, including those operating at cryogenic temperatures. The COP is defined as the amount of heat removed at the cryogenic operating temperature of the refrigerator divided by the amount of work that must be applied to remove the...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Need help comparing chest freezers and upright freezers

Currently we use in our Biobank an upright -80 freezer to store all our samples. We are planning to buy a fully automated bio-repository storage that will do the picking of samples under restricted conditions. But in the meantime I foresee that we have to pick the samples manually. The...

Need recommendations for cryogenic vials

I am looking into standardizing our range of bio storage tubes (cryogenic vials). These will be for both blood and tissue samples and their derivatives. Any recommendations, comments on Micronics, Nalgene, Nunc and or others that are suitable for long term -80 C and -196 C storage, DNA/RNA suitable, would...

We need a custom machine for flash freezing of water

We are an ice making company and have started a new project, which is related to flash freezing of water. It is based on cryogenics technology and we need a custom made machine. I would kindly ask you to pass me a few companies who would be interested in such...

Looking for a pump suitable for cold liquids

I would like to construct a small cooling circuit (appr. 50 x 50 cm) pumping liquid at a temperature down to -120°C from a cold reservoir to the specimen to be cooled. The tubes and connections are not a problem, but does somebody know a pump (suction/compression for circulation) suitable...