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Doctor Advances Cryopreservation in Heart Regeneration and Organ Transplantation

At Harvard Medical School and Massachusetts General Hospital, Dr. Rasha Al-attar’s research is at the forefront of advancing heart regeneration and organ transplantation. Initially focusing on stem cell-derived cardiomyocyte (hPSC-CM) transplantation to repair infarcted heart tissue, Dr. Al-attar faced a significant challenge: while immature hPSC-CMs survive freezing, they often induce...

Pressure Increase Method Marks Significant Advancement in Cryogenic Controls and Safety

Ensuring the integrity of packaging in cryogenic environments is crucial for maintaining product quality and operational safety. Recent advancements in non-destructive leak testing technology underscore significant improvements in cryogenic controls and safety by emphasizing the need for precise and reliable testing methods. Effective leak detection is essential for preserving the...

Tests Show High Temperature Superconducting Magnets Ready for Fusion

In the early hours of September 5, 2021, engineers at MIT’s Plasma Science and Fusion Center (PSFC) achieved a groundbreaking milestone by demonstrating a world-record magnetic field strength of 20 tesla with a new high-temperature superconducting magnet. This breakthrough is crucial for advancing fusion power technology, with the potential to...

Thermionics Laboratory Empowers Precision Nanofabrication, Ultrahigh Vacuum Manipulator for Glancing Low Angle Deposition

What does a leading optics manufacturer do when striving to develop cutting-edge lenses for high-resolution imaging systems? Their quest for flawless optical performance hinges on achieving nanostructured surfaces that minimize light scattering and maximize transmission efficiency. In the intricate world of advanced materials and nanotechnology, achieving precise fabrication techniques is...

What Is the Temperature of Space?

One of the most common questions from students when presented with an introduction to in-space applications of cryogenics is “What temperature is space?” While the askers of this question are usually enthusiastically interested, thinking space to have tactile temperatures just like the playground outside the school, this is actually a...

Beckman Institute Labs Bridge Advanced Imaging and Alzheimer’s Research

The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign has embarked on a life-changing research project to advance the early detection and diagnosis of Alzheimer’s disease. With the support of a $3 million grant from the US National Institute on Aging of the National Institutes...

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Transfer Lines

Transfer lines may in some real sense be thought of as the cryogenic fluid analogy of current leads. While current leads carry electrical power to where it’s required in a cryogenic system, transfer lines do the same with cryogenic fluids. Transfer lines range in complexity from very simple U-tubes containing...

Zero Boiloff

Zero Boil Off cryostats are those that contain liquid cryogens but are designed to eliminate or vastly reduce the boil off of  the liquid. These cryostats combine some of the advantages of Cryogen-Free systems (e.g. ease of use and long operational lifetime) with the advantages associated with a reservoir of liquid...

Cryomodule

Cryomodule is a term that is most commonly used to refer to cryostats that contain superconducting radio frequency (SRF) cavities. Such cavities are used to accelerate charged particle beams and are a major component of modern particle accelerators. Using the term cryomodule to refer to cryostats containing SRF cavities appears...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...