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Doctor Advances Cryopreservation in Heart Regeneration and Organ Transplantation

At Harvard Medical School and Massachusetts General Hospital, Dr. Rasha Al-attar’s research is at the forefront of advancing heart regeneration and organ transplantation. Initially focusing on stem cell-derived cardiomyocyte (hPSC-CM) transplantation to repair infarcted heart tissue, Dr. Al-attar faced a significant challenge: while immature hPSC-CMs survive freezing, they often induce...

Pressure Increase Method Marks Significant Advancement in Cryogenic Controls and Safety

Ensuring the integrity of packaging in cryogenic environments is crucial for maintaining product quality and operational safety. Recent advancements in non-destructive leak testing technology underscore significant improvements in cryogenic controls and safety by emphasizing the need for precise and reliable testing methods. Effective leak detection is essential for preserving the...

Tests Show High Temperature Superconducting Magnets Ready for Fusion

In the early hours of September 5, 2021, engineers at MIT’s Plasma Science and Fusion Center (PSFC) achieved a groundbreaking milestone by demonstrating a world-record magnetic field strength of 20 tesla with a new high-temperature superconducting magnet. This breakthrough is crucial for advancing fusion power technology, with the potential to...

Thermionics Laboratory Empowers Precision Nanofabrication, Ultrahigh Vacuum Manipulator for Glancing Low Angle Deposition

What does a leading optics manufacturer do when striving to develop cutting-edge lenses for high-resolution imaging systems? Their quest for flawless optical performance hinges on achieving nanostructured surfaces that minimize light scattering and maximize transmission efficiency. In the intricate world of advanced materials and nanotechnology, achieving precise fabrication techniques is...

What Is the Temperature of Space?

One of the most common questions from students when presented with an introduction to in-space applications of cryogenics is “What temperature is space?” While the askers of this question are usually enthusiastically interested, thinking space to have tactile temperatures just like the playground outside the school, this is actually a...

Beckman Institute Labs Bridge Advanced Imaging and Alzheimer’s Research

The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign has embarked on a life-changing research project to advance the early detection and diagnosis of Alzheimer’s disease. With the support of a $3 million grant from the US National Institute on Aging of the National Institutes...

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Adiabatic Demagnetization Refrigeration

Reaching temperatures below 1K requires different techniques than the various helium gas cycles found in large scale refrigeration plants and small cryocoolers. One of these techniques is Adiabatic Demagnetization Refrigeration (ADR). This technique takes advantage of the fact that the entropy of paramagnetic materials in a magnetic field is lower than...

Cryogen-Free

A cryogen is any fluid that operates at cryogenic temperatures (below roughly 150K – 120K). Using this definition, helium gas at 40K is a cryogen. Another more restrictive definition is to use cryogen to refer specifically to liquids at cryogenic temperatures. This is generally how it is used in the...

Cryostats and Cryocoolers

A cryostat is any device designed to maintain things (including fluids) at cryogenic temperatures. In general usage, cryostats tend to be passive devices rather than providing active cooling. In this usage, cryostats keep things cold by thermally isolating them from room temperature. This generally is accomplished by a combination of...

Cryogenic Treatment of Materials

F.J. Diekman Controlled Thermal Processing, Inc. info@metal-wear.com Cryogenic Processing (also called cryogenic treatment, and incorrectly “cryogenic tempering”) is a process that uses cryogenic temperatures to modify materials to enhance their performance. Cryogenic Processing involves the slow reduction in temperature of the material to at least -300°F (-185°C) and holding the...

Cryogenics in Space

Peter Kittel University of California-Berkeley pkittel@cal.berkeley.edu Space Cryogenics is the application of cryogenics to space missions. These applications fall into two broad areas, supporting space science missions and supporting the space transportation infrastructure. Science applications: The atmosphere is opaque to much of the electro-magnetic spectrum. In space, the absence of...

Cryosurgery

Review of Cryosurgery Boris Rubinsky, PhD Hebrew University School of Science and Engineering Research Center for Biomedical Engineering 78b Ross Building Givat Ram, Jerusalem 91904 Israel rubinsky@cs.huji.ac.il as published in Annual Review of Biomedical Engineering, August 2000, Vol. 2, pp. 157-187. Abstract: Cryosurgery is a surgical technique that employs freezing...

Liquefied Natural Gas

Liquefied Natural Gas as it relates to the Field of Cryogenics John W. Bonn VJ Systems, LLC johnbonn@vjsystems-lic.com Today the world is looking for a cleaner fuel and Liquefied Natural Gas (LNG) plays a large part in achieving this goal. LNG in a liquid form is at -162°C (-259°F) and...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...