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High-Resolution Cryo-EM Starts Focusing on Accessibility

Structure-based designs are integral to advancing drug discovery, and in this regard, cryogenic electron microscopy (cryo-EM) has emerged as a pivotal tool for achieving high-resolution structures of proteins and protein complexes. Particularly noteworthy is its utility in elucidating the structures of protein classes that have historically resisted crystallization. Cryo-EM’s pivotal...

Cryogenic Etch Re-Emerges

Cryogenic etch, sometimes called cryo etch, is one of two ways to enable deep silicon or high-aspect ratio (HAR) etches in devices, where the features are long, narrow and deep. The other and most popular method is the two-step Bosch process, where you etch out a part of the structure...

Tokamak Energy’s Fusion Magnet System Passes Cryogenic Tests

UK-based Tokamak Energy’s superconducting magnet system, which is being built to replicate fusion energy power plant forces, has passed significant milestone cryogenic tests. Creating fusion energy requires strong magnetic fields to confine and control the extremely hot hydrogen fuel, which becomes a plasma several times hotter than the center of...

RegO Adds Pressure Regulators for Cryogenic Vessels

RegO Products has unveiled its latest breakthrough: the CBE504 Series of Half-Inch Pressure Builder-Economizer Regulators. Designed to enhance cryogenic vessel operations, these regulators prioritize pressure control and product preservation. The CBE504 Series boasts numerous improvements over the previous CB504 model, including a more compact form factor and a broader range...

Ziath Preserves the Future, One Sample at a Time

In the realm of scientific discovery, the value of biological specimens cannot be overstated. They serve as essential windows into understanding life’s intricate mysteries. From the smallest molecules to the most complex organisms, researchers strive to unlock the secrets held within these samples. To safeguard these invaluable assets, a pioneering...

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Refrigerators and Liquefiers

Two of the most common terms used in cryogenics are “refrigerator” and “liquefier.” These terms describe similar and, as will be seen, in some cases identical components. A refrigerator provides cooling (that is, absorbs heat) at cryogenic temperatures. Refrigerators typically put a working fluid (such as helium) through one of...

Air Separation

Air separation is one of the largest, as well as earliest, industrial applications of cryogenics. In this process, cryogenic temperatures are used to separate air into its constituent gases: nitrogen (78.08%), oxygen (20.95%), argon (0.93%) and carbon dioxide (0.3%). Trace gases such as krypton, neon, xenon and helium total far...

Coefficient of Performance and Figure of Merit

The coefficient of performance (COP) is used to describe the effectiveness of refrigerators, including those operating at cryogenic temperatures. The COP is defined as the amount of heat removed at the cryogenic operating temperature of the refrigerator divided by the amount of work that must be applied to remove the...

Cryogenic Electronics

Randall Kirschman, consulting physicist, Mountain View, California ExtElect@gmail.com Cryogenic electronics—the operation of electronic devices, circuits, and systems at cryogenic temperatures—has been a valuable technology for decades. Cryogenic electronics (also referred to as low-temperature electronics, or cold electronics) can be based on semiconductive devices, on superconductive devices, or on a combination...

Particle Physics: High Energy Physics

Cryogenics and High-Energy Physics 1. From symmetry magazine: http://www.symmetrymagazine.org/cms/?pid=1000627: Cryogenics is the study of how materials behave at temperatures near absolute zero. In high-energy particle accelerators, such frigid temperatures reduce the electrical resistance of wires in superconducting magnets, increasing the magnet strength and allowing faster particle acceleration. The same holds...

HTS Degaussing Systems

From the Spring 2009 issue of Cold Facts (Volume 25, Number 2): Thanks to a joint project by the US Navy and a number of industry partners, high temperature superconducting (HTS) technology is now at the heart of an advanced degaussing system aboard the USS Higgins at the naval station...

Magnetic Resonance Imaging

From http://www.superconductors.org: An area where superconductors can perform a life-saving function is in the field of biomagnetism. Doctors need a non-invasive means of determining what’s going on inside the human body. By impinging a strong superconductor-derived magnetic field into the body, hydrogen atoms that exist in the body’s water and...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...