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Unraveling the Neutrino’s Mysteries at the Deep Underground Neutrino Experiment

Neutrinos mind their own business. Each second, billions of these fundamental particles will pass through stars, planets, buildings, and human bodies and will rarely ever be stopped by them, like a subatomic subway crowd. It’s why they’re often described as “ghostly” or “elusive.” “If scientists could create and capture the...

Berkeley Lab Scientists Develop a Cool New Method of Refrigeration

Adding salt to a road before a winter storm changes when ice will form. Researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have applied this basic concept to develop a new method of heating and cooling. The technique, which they have named “ionocaloric cooling,” is described...

With Landmark Approval, Spotlight on Cryogenic Logistics Intensifies

The cell and gene therapy (CGT) industry achieved a significant milestone at the end of 2022: the first approval of an allogeneic T-cell therapy in the world. Following a positive recommendation from Europe’s Committee for Medicinal Products for Human Use (CHMP), the European Commission on Monday 19th December formally approved Atara Biotherapeutics’ Ebvallo...

New Instrument Measures Supercurrent Flow with Quantum Benefits

Jigang Wang offered a quick walk-around of a new sort of microscope that can help researchers understand, and ultimately develop, the inner workings of quantum computing. Wang, an Iowa State University professor of physics and astronomy who’s also affiliated with the U.S. Department of Energy’s Ames National Laboratory, described how the instrument works in extreme...

Cryomech Celebrates 60 Years of Cryo-Innovations

Cryomech was founded in 1963 by William E. “Bill” Gifford. Gifford was a professor at Syracuse University from 1961 to 1978 and (in collaboration with Dr. Howard O. McMahon) invented the Gifford-McMahon (GM) cycle cryo­cooler in 1957. This invention made research at very low temperatures much more accessible to the...

The “New” Space Mission–Cryogenic Bearings

Since the late 1990s, advancements in communication technology and the advent of GPS expanded the desire for companies and governments to invest in satellite technologies that operate in higher orbit. Today, companies like SpaceX, Blue Origin, Virgin Orbit, Relativity Space and ULA are developing cost-effective, reusable launch systems.  Manufacturers understand...

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Mixed Refrigerant Cycles

Most cryogenic refrigeration systems, both large scale systems and cryocoolers, use helium as a working fluid. There are a number of advantages to helium, not the least of which is that helium remains a fluid down to the lowest achievable temperatures. In order to freeze helium, pressures of over 20...

Fountain Pumps and He II Phase Separators

Helium II (He II), the second liquid phase of the 4He isotope described in this column in Cold Facts Spring 2010 (http://2csa.us/he2), can be modeled as consisting of two interpenetrating fluids. One, the superfluid component, has zero viscosity and entropy and the other, the normal fluid component, has nonzero viscosity...

Turboexpanders

A vital technology in the refrigerators and liquefiers described in Cold Facts Volume 31 Number 3 is that of turboexpanders. These devices are rotating machines in which the process fluid (e.g., helium) does work against the turboexpander while moving from high pressure to a lower pressure and thus is cooled....

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Need help comparing chest freezers and upright freezers

Currently we use in our Biobank an upright -80 freezer to store all our samples. We are planning to buy a fully automated bio-repository storage that will do the picking of samples under restricted conditions. But in the meantime I foresee that we have to pick the samples manually. The...

Need recommendations for cryogenic vials

I am looking into standardizing our range of bio storage tubes (cryogenic vials). These will be for both blood and tissue samples and their derivatives. Any recommendations, comments on Micronics, Nalgene, Nunc and or others that are suitable for long term -80 C and -196 C storage, DNA/RNA suitable, would...

We need a custom machine for flash freezing of water

We are an ice making company and have started a new project, which is related to flash freezing of water. It is based on cryogenics technology and we need a custom made machine. I would kindly ask you to pass me a few companies who would be interested in such...

Looking for a pump suitable for cold liquids

I would like to construct a small cooling circuit (appr. 50 x 50 cm) pumping liquid at a temperature down to -120°C from a cold reservoir to the specimen to be cooled. The tubes and connections are not a problem, but does somebody know a pump (suction/compression for circulation) suitable...