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Almac Unveils New Cryogenic Service Solution for Advanced Therapy Trials

Almac Clinical Services, a member of The Almac Group, announced a new state-of-the-art cryogenic service solution within its Durham, N. C. campus to support cell and gene therapies. This latest investment from Almac adds to the company’s overall $4 million investment to date in innovative cold chain technology in North...

Air Liquide to Design Cryogenic Tanks for Vega-E Space Launcher

Air Liquide is advancing space exploration, having signed a contract with space propulsion expert Avio for the design of the new generation of cryogenic tanks for the upper stage of the future Vega-E launcher. The project is coordinated by the European Space Agency (ESA), and the launcher will use cryogenic...

Video: Pushing the Limits of Cryogenic Technology

 The extremely low temperatures required for performing state-of-the-art physics experiments and operating large quantum processors have been achieved in Project Goldeneye. IBM researchers have successfully demonstrated the proof-of-concept technology for a dilution refrigerator capable of cooling future generations of quantum experiments. You can watch a sneak peek of the IBM Quantum...

NASA’s SpaceX Crew-5 Launches to International Space Station

The crew members assigned to NASA’s SpaceX Crew-5 mission went into orbit following their launch to the International Space Station on Wednesday, October 5, from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. The international crew will serve as the agency’s fifth commercial crew rotation mission with SpaceX...

Cryogenic Blast Freezing in Minutes Increases Throughput

The biotech and biopharma industries utilize freezers to rapidly freeze and store thermally sensitive products such as vaccines and biopharmaceuticals as well as biological materials such as blood plasma. However, conventional compressor-based systems can take hours to reach an ultra-low target temperature, which slows production throughput.  For these industries, the...

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Cold Compressors

A common way to provide cooling below the normal boiling point of helium (4.2K) is to reduce the pressure above the bath of liquid helium, thus also reducing the bath’s equilibrium saturation temperature. For example, to produce a 1.8K bath of liquid helium, the saturation pressure has to be reduced...

Kapitza Conductance

Kapitza conductance refers to the heat transfer between a solid surface and a fluid that covers that surface. Fundamentally, it describes the inherent difficulty in transferring energy from a solid to the fluid covering the solid surface. This phenomenon was first observed by P. L. Kapitza in 1941 while studying...

Thermosyphons

A thermosyphon (or thermosiphon) is a device that transfers heat via natural convection in a fluid. The natural convection is driven by gravity with the colder, denser fluid flowing downhill and the warmer, less dense fluid flowing back up. Thus, thermosyphons connect an object to be cooled with a reservoir...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Need help comparing chest freezers and upright freezers

Currently we use in our Biobank an upright -80 freezer to store all our samples. We are planning to buy a fully automated bio-repository storage that will do the picking of samples under restricted conditions. But in the meantime I foresee that we have to pick the samples manually. The...

Need recommendations for cryogenic vials

I am looking into standardizing our range of bio storage tubes (cryogenic vials). These will be for both blood and tissue samples and their derivatives. Any recommendations, comments on Micronics, Nalgene, Nunc and or others that are suitable for long term -80 C and -196 C storage, DNA/RNA suitable, would...

We need a custom machine for flash freezing of water

We are an ice making company and have started a new project, which is related to flash freezing of water. It is based on cryogenics technology and we need a custom made machine. I would kindly ask you to pass me a few companies who would be interested in such...

Looking for a pump suitable for cold liquids

I would like to construct a small cooling circuit (appr. 50 x 50 cm) pumping liquid at a temperature down to -120°C from a cold reservoir to the specimen to be cooled. The tubes and connections are not a problem, but does somebody know a pump (suction/compression for circulation) suitable...