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Almac Unveils New Cryogenic Service Solution for Advanced Therapy Trials

Almac Clinical Services, a member of The Almac Group, announced a new state-of-the-art cryogenic service solution within its Durham, N. C. campus to support cell and gene therapies. This latest investment from Almac adds to the company’s overall $4 million investment to date in innovative cold chain technology in North...

Cryo-EM Reveals Cold-sensing Cell Channels Manipulated by Chemicals to Induce Cold Sensation

A team of researchers affiliated with the Duke University School of Medicine, Lehigh University and the National Institutes of Health has revealed the molecular means by which cold-sensing channels in cells are manipulated by certain chemicals to induce a cold sensation. The study is published in the journal Science. Prior research...

Air Liquide to Design Cryogenic Tanks for Vega-E Space Launcher

Air Liquide is advancing space exploration, having signed a contract with space propulsion expert Avio for the design of the new generation of cryogenic tanks for the upper stage of the future Vega-E launcher. The project is coordinated by the European Space Agency (ESA), and the launcher will use cryogenic...

Video: Pushing the Limits of Cryogenic Technology

The extremely low temperatures required for performing state-of-the-art physics experiments and operating large quantum processors have been achieved in Project Goldeneye. IBM researchers have successfully demonstrated the proof-of-concept technology for a dilution refrigerator capable of cooling future generations of quantum experiments. You can watch a sneak peek of the IBM Quantum...

NASA’s SpaceX Crew-5 Launches to International Space Station

The crew members assigned to NASA’s SpaceX Crew-5 mission went into orbit following their launch to the International Space Station on Wednesday, October 5, from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. The international crew will serve as the agency’s fifth commercial crew rotation mission with SpaceX...

Cryogenic Blast Freezing in Minutes Increases Throughput

The biotech and biopharma industries utilize freezers to rapidly freeze and store thermally sensitive products such as vaccines and biopharmaceuticals as well as biological materials such as blood plasma. However, conventional compressor-based systems can take hours to reach an ultra-low target temperature, which slows production throughput. For these industries, the...

Latest in Defining Cryogenics

Adiabatic Demagnetization Refrigeration

Reaching temperatures below 1K requires different techniques than the various helium gas cycles found in large scale refrigeration plants and small cryocoolers. One of these techniques is Adiabatic Demagnetization Refrigeration (ADR). This technique takes advantage of the fact that the entropy of paramagnetic materials in a magnetic field is lower than...

Cryogen-Free

A cryogen is any fluid that operates at cryogenic temperatures (below roughly 150K – 120K). Using this definition, helium gas at 40K is a cryogen. Another more restrictive definition is to use cryogen to refer specifically to liquids at cryogenic temperatures. This is generally how it is used in the...

Cryostats and Cryocoolers

A cryostat is any device designed to maintain things (including fluids) at cryogenic temperatures. In general usage, cryostats tend to be passive devices rather than providing active cooling. In this usage, cryostats keep things cold by thermally isolating them from room temperature. This generally is accomplished by a combination of...

Latest in Cryo Central

History of Cryogenics

From the Fall 1999 issue of Cold Facts magazine Millennium Breakthroughs A variety of CSA members give different perspectives on the past millennium: What were the most significant breakthroughs in cryogenics during the past millennium? Prof. R.G. Scurlock, Kryos Technology, scurlock@soton.ac.uk (“Breakthrough” = way through obstacles — Oxford English Dictionary)...

Cryobiology

Andreas Sputtek Past President Society for Cryobiology sputtek@uke.uni-hamburg.de or http://www.sputtek.de/. The word cryobiology (from the Greek words “cryo” = cold, “bios” = life, and “logos” = science) literally signifies the science of life at low temperatures. In practice, this field comprises the study of any biological material or system (e.g.,...

Cryogenic Insulation

James E. Fesmire Cryogenics Test Laboratory NASA Kennedy Space Center james.e.fesmire@nasa.gov Introduction In today’s world, the use of cryogenics and low-temperature refrigeration is taking a more and more significant role. From the food industry, transportation, energy, and medical applications to the Space Shuttle, cryogenic liquids must be stored, handled, and...

Cryogenic Treatment of Materials

F.J. Diekman Controlled Thermal Processing, Inc. info@metal-wear.com Cryogenic Processing (also called cryogenic treatment, and incorrectly “cryogenic tempering”) is a process that uses cryogenic temperatures to modify materials to enhance their performance. Cryogenic Processing involves the slow reduction in temperature of the material to at least -300°F (-185°C) and holding the...

Latest in Ask the Experts

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...

Separated layers of ice over a pipe

I want to know that why there are different layers of ice over a pipe carrying a cryogenic fluid, each layer separated with clear marks / lines? What do these layers signify?

Using nitrogen as a cryogen

Is it possible to achieve -200˚C using nitrogen as a cryogen?

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