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New Microscope Advances Cryo-ET Research

Thermo Fisher Scientific Inc. unveiled the Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (Cryo-PFIB), a new connected and automated microscope designed to advance the pace of cryo-electron tomography (cryo-ET) research. Cryo-ET makes it possible to study how proteins and other molecules operate together in a cellular context, at resolutions unsurpassed by...

Excavation of Huge Caverns for DUNE Particle Detector Underway

Around a mile below the surface in South Dakota, construction crews are hard at work excavating around 1,000 tons of rock per day. Their goal is to make room for a large underground facility that will house an international effort aimed at studying neutrinos—highly elusive subatomic particles that may hold...

In DNA–Scientists find solution to building superconductor that could transform technology

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.  One possible outcome of such engineered materials could be superconductors, which have zero electrical resistance, allowing electrons to flow unimpeded. That means...

Researchers Take First-Ever Cryo-EM Images of Nitrogenase in Action

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action. Now, for the first time, researchers at the University of California San Diego report near-atomic-resolution snapshots of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM). The...

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Transfer Lines

Transfer lines may in some real sense be thought of as the cryogenic fluid analogy of current leads. While current leads carry electrical power to where it’s required in a cryogenic system, transfer lines do the same with cryogenic fluids. Transfer lines range in complexity from very simple U-tubes containing...

Zero Boiloff

Zero Boil Off cryostats are those that contain liquid cryogens but are designed to eliminate or vastly reduce the boil off of  the liquid. These cryostats combine some of the advantages of Cryogen-Free systems (e.g. ease of use and long operational lifetime) with the advantages associated with a reservoir of liquid...

Cryomodule

Cryomodule is a term that is most commonly used to refer to cryostats that contain superconducting radio frequency (SRF) cavities. Such cavities are used to accelerate charged particle beams and are a major component of modern particle accelerators. Using the term cryomodule to refer to cryostats containing SRF cavities appears...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

Designing a liquid oxygen bath

I’m designing a Liquid Oxygen Bath to place composite coupons in the bath and soak 96 samples for intervals of 8 hours, 24 hours, 7 days, 21 days, 42 days, 62 days and 90 days.

Metallic Salts Normally Used to Produce Ultra-Low Temperatures?

Regarding the method known as the Adiabatic Demagnetization of Paramagnetic Salts: What metallic salts are normally used to produce the ultra-low temperatures used for near-absolute-zero cryogenic research? Which salts are the most efficient? Which make the best cooling agents? And which are used most commonly by physicists? I am looking...