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Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Cryogenic Technique Reveals Fraudulent Food and Drugs

Engineers from the University of California, Riverside have developed "chronoprinting," a new technique that can detect fake drugs and food using videos recorded while samples undergo alterations. The technology requires only a few relatively inexpensive pieces of equipment, free software to accurately distinguish pure from inferior food or medicine and...

NASA’s JPL Seeking Applicants for First Space Accelerator

NASA's first aerospace accelerator program will select 10 startup companies to take part in a three-month pilot program to develop new technologies for space. Applications will be accepted through April 7. Selected teams will develop concepts and business plans over a three-month period and then pitch their results to the...

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Dilution Refrigerators

Dilution refrigerators are a common technique for reaching temperatures below 1K, particularly where continuous cooling at these temperatures is required. Helium exists in two stable isotopes: 4He and 3He. Naturally occurring 3He is extremely rare, constituting less than 1 part per million of helium gas. However, 3He can be manufactured,...

Oxygen Deficiency Hazards

Oxygen Deficiency Hazards (ODH) are a significant safety issue in cryogenic facilities. ODH occurs when inert gases such as nitrogen, helium or argon displace room air and thus lower the percentage of oxygen in the space below that required for human life. OSHA defines an area as oxygen deficient if...

Kelvin Temperature Scale

The Kelvin temperature scale is the principal temperature scale used in cryogenics and science. The kelvin is also one of the seven base units in the Système International d’Unités (SI) and is the unit of thermodynamic temperature. Thermodynamic temperature is a fundamental physical quantity (like mass, length or electrical current)...

Magnets

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. Particle physics uses accelerators to recreate the conditions of the early universe in an attempt to piece together the complex puzzle of how we got to where we are today. These huge machines are used...

Energy Storage

From “Superconductivity: Present and Future Applications” by the Coalition for the Commercial Application of Superconductors. With power lines increasingly congested and prone to instability, strategic injection of brief bursts of real power can play a crucial role in maintaining grid reliability. Small-scale Superconducting Magnetic Energy Storage (SMES) systems, based on...

Astronomy

ASTRONOMY IN SPACE by Peter V. Mason, retired,  Jet Propulsion Laboratory, and Visiting Associate, California Institute of Technology. Pmason@alumni.caltech.edu In thinking about the reasons to perform astronomy in space, we first consider the effect of the earth’s atmosphere.  On a scale of decreasing energy, gamma rays, cosmic rays, X-rays and...

Cryocoolers

What is a Cryocooler? A mechanism that can extract heat from an object (cooler) and by doing so draw its temperature down below approximately 150 Kelvin (cryo). — (Courtesy Dr. Willy Gully) What is the difference between a Cryocooler and a Cryostat? A cryostat is any device designed to maintain...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...