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Cryo-EM Reveals Crucial Electrical Switch in Brain

Scientists using cryo-EM have revealed the structure of a critical receptor (AMPA) in the brain associated with learning, memory, behavior and mood. The research was also the first to reveal the structure of AMPA receptors in a natural state, a discovery that could lead to new insight about the mechanism...

Researchers Discover Water that Never Freezes

Can water reach -263°C without turning into ice? The answer is yes, according to a group of physicists and chemists from ETH Zurich and the University of Zurich who identified an unusual way to not only prevent water from forming ice crystals while at extreme sub-zero temperatures but to also...

Working Together as a “virtual telescope,” Observatories Around the World Produce First Direct Images of a Black Hole

MIT News reported on April 10 that an international team of over 200 astronomers had captured the first direct images of a black hole. They accomplished this remarkable feat by coordinating the power of nine major radio observatories on four continents, to work together as a virtual, Earth-sized telescope. In...

Turning Patient Cells into Cancer Fighters

Cancer therapy could soon include a personalized cancer treatment based on engineered immune cells derived from a patient's individual cells. The approach involves attaching proteins to these cells, receptors that target antigens present in cancer cells to then enable a patient’s immune system to seek out and destroy tumors.

Cold Atoms Act as Distant Messengers

Particles can interact directly by repelling or attracting each other, but how do particles interact when far apart? Scientists at the University of Chicago have discovered that atoms can actually exchange information using intermediary particles. Such research represents the first time this particular phenomenon has been observed in a cold...

Cryo-EM Helps Decipher 3D Structure for Cancer Treatment

A research team from Columbia University and Nimbus Therapeutics has successfully determined the 3D structure of human ATP-citrate lyase (ACLY), a metabolic enzyme that plays a key role in cancer cell proliferation and other cellular processes.

Latest in Defining Cryogenics

Dilution Refrigerators

Dilution refrigerators are a common technique for reaching temperatures below 1K, particularly where continuous cooling at these temperatures is required. Helium exists in two stable isotopes: 4He and 3He. Naturally occurring 3He is extremely rare, constituting less than 1 part per million of helium gas. However, 3He can be manufactured,...

Oxygen Deficiency Hazards

Oxygen Deficiency Hazards (ODH) are a significant safety issue in cryogenic facilities. ODH occurs when inert gases such as nitrogen, helium or argon displace room air and thus lower the percentage of oxygen in the space below that required for human life. OSHA defines an area as oxygen deficient if...

Kelvin Temperature Scale

The Kelvin temperature scale is the principal temperature scale used in cryogenics and science. The kelvin is also one of the seven base units in the Système International d’Unités (SI) and is the unit of thermodynamic temperature. Thermodynamic temperature is a fundamental physical quantity (like mass, length or electrical current)...

Latest in Cryo Central

Cryogenic Electronics

Randall Kirschman, consulting physicist, Mountain View, California ExtElect@gmail.com Cryogenic electronics—the operation of electronic devices, circuits, and systems at cryogenic temperatures—has been a valuable technology for decades. Cryogenic electronics (also referred to as low-temperature electronics, or cold electronics) can be based on semiconductive devices, on superconductive devices, or on a combination...

Particle Physics: High Energy Physics

Cryogenics and High-Energy Physics 1. From symmetry magazine: http://www.symmetrymagazine.org/cms/?pid=1000627: Cryogenics is the study of how materials behave at temperatures near absolute zero. In high-energy particle accelerators, such frigid temperatures reduce the electrical resistance of wires in superconducting magnets, increasing the magnet strength and allowing faster particle acceleration. The same holds...

HTS Degaussing Systems

From the Spring 2009 issue of Cold Facts (Volume 25, Number 2): Thanks to a joint project by the US Navy and a number of industry partners, high temperature superconducting (HTS) technology is now at the heart of an advanced degaussing system aboard the USS Higgins at the naval station...

Magnetic Resonance Imaging

From http://www.superconductors.org: An area where superconductors can perform a life-saving function is in the field of biomagnetism. Doctors need a non-invasive means of determining what’s going on inside the human body. By impinging a strong superconductor-derived magnetic field into the body, hydrogen atoms that exist in the body’s water and...

Latest in Ask the Experts

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...

Separated layers of ice over a pipe

I want to know that why there are different layers of ice over a pipe carrying a cryogenic fluid, each layer separated with clear marks / lines? What do these layers signify?

Using nitrogen as a cryogen

Is it possible to achieve -200˚C using nitrogen as a cryogen?

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