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Almac Unveils New Cryogenic Service Solution for Advanced Therapy Trials

Almac Clinical Services, a member of The Almac Group, announced a new state-of-the-art cryogenic service solution within its Durham, N. C. campus to support cell and gene therapies. This latest investment from Almac adds to the company’s overall $4 million investment to date in innovative cold chain technology in North...

Air Liquide to Design Cryogenic Tanks for Vega-E Space Launcher

Air Liquide is advancing space exploration, having signed a contract with space propulsion expert Avio for the design of the new generation of cryogenic tanks for the upper stage of the future Vega-E launcher. The project is coordinated by the European Space Agency (ESA), and the launcher will use cryogenic...

Video: Pushing the Limits of Cryogenic Technology

 The extremely low temperatures required for performing state-of-the-art physics experiments and operating large quantum processors have been achieved in Project Goldeneye. IBM researchers have successfully demonstrated the proof-of-concept technology for a dilution refrigerator capable of cooling future generations of quantum experiments. You can watch a sneak peek of the IBM Quantum...

NASA’s SpaceX Crew-5 Launches to International Space Station

The crew members assigned to NASA’s SpaceX Crew-5 mission went into orbit following their launch to the International Space Station on Wednesday, October 5, from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. The international crew will serve as the agency’s fifth commercial crew rotation mission with SpaceX...

Cryogenic Blast Freezing in Minutes Increases Throughput

The biotech and biopharma industries utilize freezers to rapidly freeze and store thermally sensitive products such as vaccines and biopharmaceuticals as well as biological materials such as blood plasma. However, conventional compressor-based systems can take hours to reach an ultra-low target temperature, which slows production throughput.  For these industries, the...

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Adiabatic Demagnetization Refrigeration

Reaching temperatures below 1K requires different techniques than the various helium gas cycles found in large scale refrigeration plants and small cryocoolers. One of these techniques is Adiabatic Demagnetization Refrigeration (ADR). This technique takes advantage of the fact that the entropy of paramagnetic materials in a magnetic field is lower than...

Cryogen-Free

A cryogen is any fluid that operates at cryogenic temperatures (below roughly 150K – 120K). Using this definition, helium gas at 40K is a cryogen. Another more restrictive definition is to use cryogen to refer specifically to liquids at cryogenic temperatures. This is generally how it is used in the...

Cryostats and Cryocoolers

A cryostat is any device designed to maintain things (including fluids) at cryogenic temperatures. In general usage, cryostats tend to be passive devices rather than providing active cooling. In this usage, cryostats keep things cold by thermally isolating them from room temperature. This generally is accomplished by a combination of...

Air Separation and Liquefaction

by Nils Tellier, PE, President, EPSIM Corporation (CSA CSM) nils@epsim.us All illustrations courtesy EPSIM Corporation Background History of Air Separation and Liquefaction This section builds on a rich history of methods to develop deep refrigeration and cryogenic liquefaction during the 19th Century. You are encouraged to read Cryo Central’s History...

Bose-Einstein Condensate

A Bose-Einstein condensate, first proposed in 1925 by Albert Einstein based on work done by Satyendra Nath Bose (the same Bose from whom the term boson is derived), is a super-cold state of matter in which almost all of the individual atoms have “condensed” down to the lowest possible quantum...

Cold Technology for Pest Control

While it does not reach temperatures cold enough to be called cryogenic, carbon dioxide snow is at the heart of a new way of dealing with unwanted pests. It utilizes a quick freezing process that takes advantage of the properties of carbon dioxide snow and has a number of benefits...

Cryogenic Finishing

The following 3 articles discuss the uses and procedures of various type of cryogenic finishing. 1) By Robin A. Rhodes, Cryogenic Institute of New England, Inc. rrhodes@nitrofreeze.com Cryogenic Deflashing is employed to remove undesired residual mold flash that remains on molded parts after they are removed or ejected from the...

An Issue of Pressure and Flow Rate in a Supply Tank

Please help solve this problem: A supply tank requires a vaporizer to generate sufficient pressure to pump stored fluid up into a vehicle or tank. The available head is limited as the tank level falls and it is important to minimize the system pressure drop to maintain the desired flow...

Using MLI on VJ Line Joints or Cryo Storage Tanks

When installing Multi Layer Insulation (MLI) blankets on VJ line joints or cryo storage tanks should they be wrapped and tied down tight or loose? These are usually pre-cut to size. Also should they have an access hole at the point of where the molecular sieve is installed to help...